HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …

5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous
system and peripheral structures, acting also as a hormone in platelets. Although its …

Although drugs are intended to be selective, at least some bind to several physiological
targets, explaining side effects and efficacy. Because many drug–target combinations exist …

It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …

Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its
effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors …

Serotonin (5-hydroxytryptamine; 5-HT) is a monoamine neurotransmitter whose effects are
mediated by at least 13 distinct G protein-coupled receptors (GPCRs) of the type A family …

Serotonin Receptors – From Molecular Biology to Clinical Applications Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2011 …

The main class of atypical antipsychotic drugs (APDs) in current use includes the protypical
atypical APD, clozapine, as well as aripiprazole, asenapine, iloperidone, lurasidone …

This systematic review summarizes pharmacogenetic studies on antidepressant response
and side effects. Out of the 17 genes we reviewed, 8 genes were entered into the meta …

The serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into 7 subfamilies
by convention, 6 of which include 13 different genes for G-protein-coupled receptors. Those …