Multiple layers of vascular smooth muscle cells (vSMCs) are present in blood vessels
forming the media of the vessel wall. vSMCs provide a vessel wall structure, enabling it to …

Complex multicellular life in mammals relies on functional cooperation of different organs for
the survival of the whole organism. The kidneys play a critical part in this process through …

Atherosclerosis is characterized by the plaque formation that restricts intraarterial blood flow.
The disturbed blood flow with the associated oscillatory stress (OS) at the arterial curvatures …

Recent studies suggest that training of innate immune cells such as tissue-resident
macrophages by repeated noxious stimuli can heighten host defense responses. However …

Endothelial cells line the blood and lymphatic vasculature, and act as an essential physical
barrier, control nutrient transport, facilitate tissue immunosurveillance and coordinate …

Background Angiogenesis, a basic requirement for tumor cell survival, is considered to be a
malignant characteristic of small cell lung cancer (SCLC) and is closely related to the poor …

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease. BAF60c, a unique
subunit of the SWItch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex, is …

Vascular endothelial cells (ECs) sense and respond to hemodynamic forces such as
pulsatile shear stress (PS) and oscillatory shear stress (OS). Among the metabolic pathways …

Nanomaterials (NMs) with tubular structures, such as halloysite nanotubes (HNTs), have
potential applications in biomedicine. Although the biocompatibility of HNTs has been …

Krüppel-like factor 4 (KLF4), a zinc finger transcription factor, is found in different human
tissues and shows diverse regulatory activities in a cell-dependent manner. In the brain …