BACKGROUND: The IF protein nestin and the RNA-binding protein musashi are expressed
by neural progenitor cells during CNS development. Their expression in glial tumors was …

By serial transplantation of human glioblastoma biopsies into the brain of immunodeficient
nude rats, two different tumor phenotypes were obtained. Initially, the transplanted …

OBJECTIVE: The purpose of this study was to use computational modeling to better
understand factors that impact neural recordings with silicon microelectrodes used in brain …

Advanced fabrication techniques have now made it possible to produce microelectrode
arrays for recording the electrical activity of a large number of neurons in the intact brain for …

Background Establishing clinically relevant animal models of glioblastoma multiforme (GBM)
remains a challenge, and many commonly used cell line-based models do not recapitulate …

This study describes the biological effects of hyperoxic treatment on BT4C rat glioma
xenografts in vivo with special reference to tumor growth, angiogenesis, apoptosis, general …

Introduction: Adequate animal glioma models are mandatory for the pursuit of preclinical
research in neuro-oncology. Many implantation models have been described, but none …

Purpose: We investigated the capability of small animal imaging in clinical scanners for
cancer research focusing on positron emission tomography (PET), computed tomography …

We have previously established two distinct glioma phenotypes by serial
xenotransplantation of human glioblastoma (GBM) biopsies in nude rats. These tumors …

Background Quantifying tumor growth and treatment response noninvasively poses a
challenge to all experimental tumor models. The aim of our study was, to assess the value of …