Incorporation of hydroxyapatite (HA) within a degradable polymeric scaffold may provide a favorable synthetic microenvironment that more closely mimics natural bone tissue …
MA Yassin, KN Leknes, TO Pedersen… - … Research Part A, 2015 - Wiley Online Library
Constructs intended for bone tissue engineering (TE) are influenced by the initial cell seeding density. Therefore, the objective of this study was to determine the effect of bone …
Decellularized organ scaffolds allow whole organ regeneration and study of cell behavior in three-dimensional culture conditions. Cell viability within the bio-engineered organ …
AM Permlid, P Roci, E Fredlund, F Fält, E Önell… - Toxicology in Vitro, 2019 - Elsevier
Two-dimensional cell culturing has proven inadequate as a reliable preclinical tumour model due to many inherent limitations. Hence, novel three-dimensional (3D) cell culture …
E Fiorentini, D Granchi, E Leonardi… - … Journal of Artificial …, 2011 - journals.sagepub.com
Purpose For bone regeneration therapy using stem cells, well-defined ex vivo protocols to expand mesenchymal stromal cells (MSC), as well as assays to show their potential …
X Zhou, I Holsbeeks, S Impens, M Sonnaert… - … Engineering Part C …, 2013 - liebertpub.com
Bone tissue engineering (TE) aims to develop reproducible and predictive three- dimensional (3D) TE constructs, defined as cell-seeded scaffolds produced by a controlled …
R Martins, TM Cestari, RVN Arantes… - Journal of …, 2018 - Wiley Online Library
Objectives This study compares the osseointegration of machined‐zirconia implants containing yttria (M‐Y‐TZP) with machined (M‐Ti) and resorbable blast media (RBM‐Ti) …
CR Rathbone, T Guda, BM Singleton… - … Research Part A, 2014 - Wiley Online Library
Highly porous hydroxyapatite (HA) scaffolds were developed as bone graft substitutes using a template coating process, characterized, and seeded with bone marrow‐derived …
Maintaining cell viability within 3D tissue engineering scaffolds is an essential step toward a functional tissue or organ. Assessment of cell viability in 3D scaffolds is necessary to control …