Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development
N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …
soluble recombinant antigens by stronger protective immunogenicity associated with the …
Virus-like particles: the new frontier of vaccines for animal viral infections
Vaccination continues to be the main approach to protect animals from infectious diseases.
Until recently, all licensed vaccines were developed using conventional technologies …
Until recently, all licensed vaccines were developed using conventional technologies …
Development of virus-like particle technology from small highly symmetric to large complex virus-like particle structures
P Pushko, P Pumpens, E Grens - Intervirology, 2013 - karger.com
Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …
Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics
Nipah virus (NiV) causes severe encephalitis in humans. Three NiV strains NiV‐Malaysia
(NiVM), NiV Bangladesh (NiVB), and NiV India (NiVI reported in 2019) have been circulating …
(NiVM), NiV Bangladesh (NiVB), and NiV India (NiVI reported in 2019) have been circulating …
A prime-boost strategy using virus-like particles pseudotyped for HCV proteins triggers broadly neutralizing antibodies in macaques
P Garrone, AC Fluckiger, PE Mangeot… - Science translational …, 2011 - science.org
Chronic hepatitis C virus (HCV) infection, with its cohort of life-threatening complications,
affects more than 200 million persons worldwide and has a prevalence of more than 10% in …
affects more than 200 million persons worldwide and has a prevalence of more than 10% in …
Non-viral nucleic acid delivery methods
I Slivac, D Guay, M Mangion, J Champeil… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Delivery of nucleic acid-based molecules in human cells is a highly studied
approach for the treatment of several disorders including monogenic diseases and cancers …
approach for the treatment of several disorders including monogenic diseases and cancers …
Nanoparticles as adjuvants in vaccine delivery
A Garg, HK Dewangan - Critical Reviews™ in Therapeutic …, 2020 - dl.begellhouse.com
Nanotechnology provides an excellent platform for the development of a new generation of
vaccines. These are based on purified subunit proteins or polysaccharides, recombinant …
vaccines. These are based on purified subunit proteins or polysaccharides, recombinant …
Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development
Highlights▶ Microorganisms are inexpensive platforms to produce chimeric VLPs.▶
Bacteriophage-derived VLPs are excellent structures for drug delivery.▶ Microbial cell …
Bacteriophage-derived VLPs are excellent structures for drug delivery.▶ Microbial cell …
The MultiBac baculovirus/insect cell expression vector system for producing complex protein biologics
Multiprotein complexes regulate most if not all cellular functions. Elucidating the structure
and function of these complex cellular machines is essential for understanding biology …
and function of these complex cellular machines is essential for understanding biology …
Rift Valley fever virus structural proteins: expression, characterization and assembly of recombinant proteins
Abstract Background Studies on Rift Valley Fever Virus (RVFV) infection process and
morphogenesis have been hampered due to the biosafety conditions required to handle this …
morphogenesis have been hampered due to the biosafety conditions required to handle this …