Background: Esophageal cancer (EC) occurs commonly, especially in Asia, and is the sixth
leading cause of cancer deaths worldwide. Recently, great progress has been made in …

Simple Summary Esophageal cancer holds the rank of 6th highest mortality rate worldwide
and carries a low survival rate of 10–30%. The pathology type of esophageal squamous cell …

Even distinct cancer types share biological hallmarks. Here, we investigate polygenic risk
score (PRS)-specific pleiotropy across 16 cancers in European ancestry individuals from the …

Objective In the past few decades, more than 500 reports have been published on the
relationship between single nucleotide polymorphisms (SNPs) on candidate genes and …

Background: There exists compelling evidence that some genetic variants are associated
with the risk of multiple cancer sites (ie, pleiotropy). However, the biological mechanisms …

An increasing number of publications had reported the association between single‐
nucleotide polymorphisms (SNPs) and esophageal cancer (EC) risk in the past decades …

Background There are several meta-analyses on the genetic relationship between the
rs1695 polymorphism within the GSTP1 (glutathione S-transferase pi 1) gene and the risk of …

Developmental dyslexia is a complex reading and writing disorder with strong genetic
components. In previous genetic studies about dyslexia, a number of candidate genes have …

Objective: Vascular Endothelial Growth Factor (VEGF) plays an important role in tumor
angiogenesis. Although several studies revealed on association of VEGF polymorphisms …

Background Due to differences in genetic background, it is unclear whether the genetic loci
identified by the previous genome-wide association studies (GWAS) of pancreatic cancer …