Endocytic trafficking relies on highly localized events in cell membranes. Endocytosis
involves the gathering of protein (cargo/receptor) at distinct plasma membrane locations …

Motor proteins are key players in exerting spatiotemporal control over the intracellular
location of membrane-bound compartments, including endosomes containing cargo. In this …

Lysosomes are essential for cellular recycling, nutrient signaling, autophagy, and
pathogenic bacteria and viruses invasion. Lysosomal fusion is fundamental to cell survival …

Intracellular transcytosis can enhance the penetration of nanomedicines to deep avascular
tumor tissues, but strategies that can improve transcytosis are limited. In this study, we …

Legionella pneumophila grows intracellularly within the membrane-bound Legionella-
containing vacuole (LCV) established by proteins translocated via the bacterial type IV …

Vesicular transport driven by membrane trafficking systems conserved in eukaryotes is
critical to cellular functionality and homeostasis. It is known that homotypic fusion and …

Endocytosis and recycling control the uptake and retrieval of various materials, including
membrane proteins and lipids, in all eukaryotic cells. These processes are crucial for cell …

Cargo delivery from one compartment to the next relies on the fusion of vesicles with
different cellular organelles in a process that requires the concerted action of tethering …

Intercellular communication is an essential process in all multicellular organisms. During this
process, molecules secreted by one cell will bind to a receptor on the cognate cell leading to …

Simple Summary The small GTPase RAB11 is a master regulator of both vesicular trafficking
and membrane dynamic defining the surface proteome of cellular membranes. As a …