HIF-1α in osteoarthritis: from pathogenesis to therapeutic implications

CY Zeng, XF Wang, FZ Hua - Frontiers in Pharmacology, 2022 - frontiersin.org
Osteoarthritis is a common age-related joint degenerative disease. Pain, swelling, brief
morning stiffness, and functional limitations are its main characteristics. There are still no …

Bioresorbable Chitosan-Based Bone Regeneration Scaffold Using Various Bioceramics and the Alteration of Photoinitiator Concentration in an Extended UV …

FA Azaman, K Zhou, MM Blanes-Martínez… - Gels, 2022 - mdpi.com
Bone tissue engineering (BTE) is an ongoing field of research based on clinical needs to
treat delayed and non-union long bone fractures. An ideal tissue engineering scaffold …

Design of a mechanobioreactor to apply anisotropic, biaxial strain to large thin biomaterials for tissue engineered heart valve applications

E Wong, S Parvin Nejad, KA D'Costa… - Annals of biomedical …, 2022 - Springer
Repair and replacement solutions for congenitally diseased heart valves capable of post-
surgery growth and adaptation have remained elusive. Tissue engineered heart valves …

Strong and tough β-TCP/PCL composite scaffolds with gradient structure for bone tissue engineering: Development and evaluation

X Shao, Y Wu, M Ding, X Chen, T Zhou, C Huang… - Ceramics …, 2024 - Elsevier
Bioactive ceramic bone scaffolds are limited by their brittleness. To address this limitation,
we developed a new method for preparing β-tricalcium phosphate (β-TCP)/polycaprolactone …

Early resistance rehabilitation improves functional regeneration following segmental bone defect injury

KE Williams, JA Harrer, SA LaBelle… - npj Regenerative …, 2024 - nature.com
Many studies have explored different loading and rehabilitation strategies, yet rehabilitation
intensity and its impact on the local strain environment and bone healing have largely not …

[HTML][HTML] How controlled motion alters the biophysical properties of musculoskeletal tissue architecture

M Hardy, L Feehan, G Savvides, J Wong - Journal of Hand Therapy, 2023 - Elsevier
Introduction Movement is fundamental to the normal behaviour of the hand, not only for day-
to-day activity, but also for fundamental processes like development, tissue homeostasis and …

Biomechanics in clinical application for bone diseases

Y Niu, Y Wang, H Meng, C Yin, K Dang… - Bone Cell Biomechanics …, 2024 - Elsevier
Biomechanics provides research methods for researchers and clinical workers to reveal the
occurrence and development of bone diseases and develop treatment and prevention …

New Ground-Breaking Strategies in Bone Regeneration—In Memory of Nerio Ceroni

A De Vita, DM Donati, L Mercatali, T Ibrahim - Biomedicines, 2022 - mdpi.com
The complex biological mechanisms which orchestrate bone homeostasis are represented
by a balance between bone formation and bone resorption, which persists for all of life. In …

Conceptual Design and Preliminary Experiment of an Orthopedic Rehabilitation Exoskeleton Based on the Coupled Movable Pulley Mechanism (CMPM)

Y Ji, X Lang, B Wu, Y Fan, Q Zheng… - 2024 World …, 2024 - ieeexplore.ieee.org
During the bone tissue proliferative phase following fracture surgery, axial mechanical
stimulation has been shown to facilitate bone healing. This study introduces the mechanism …

Design of a Novel Biaxial Mechanobioreactor and Ultrasound-Based, Non-Destructive Testing Platform for Pediatric Heart Valve Engineering

EKY Wong - 2024 - search.proquest.com
Currently, no solutions with the capacity for growth and adaptation exist for replacing heart
valves with congenital defects. Tissue engineered heart valves (TEHVs) offer a biological …