The adverse effects of air pollution on the eye: a review

CC Lin, CC Chiu, PY Lee, KJ Chen, CX He… - International journal of …, 2022 - mdpi.com
Air pollution is inevitably the result of human civilization, industrialization, and globalization.
It is composed of a mixture of gases and particles at harmful levels. Particulate matter (PM) …

[HTML][HTML] Iron accumulation and lipid peroxidation in the aging retina: implication of ferroptosis in age-related macular degeneration

T Zhao, X Guo, Y Sun - Aging and disease, 2021 - ncbi.nlm.nih.gov
Iron is an essential component in many biological processes in the human body. It is critical
for the visual phototransduction cascade in the retina. However, excess iron can be toxic …

[HTML][HTML] Advanced human developmental toxicity and teratogenicity assessment using human organoid models

M Li, J Gong, L Gao, T Zou, J Kang, H Xu - … and Environmental Safety, 2022 - Elsevier
Tremendous progress has been made in the field of toxicology leading to the advance of
developmental toxicity assessment. Conventional animal models and in vitro two …

Airborne fine particulate matter (PM2. 5) damages the inner blood–retinal barrier by inducing inflammation and ferroptosis in retinal vascular endothelial cells

Y Gu, S Hao, K Liu, M Gao, B Lu, F Sheng… - Science of The Total …, 2022 - Elsevier
This study was the first to explore the effect of airborne fine particulate matter (PM 2.5)
exposure on the inner blood–retinal barrier (iBRB). In this study, retinal vascular …

The impact of particulate matter (PM2. 5) on human retinal development in hESC-derived retinal organoids

Y Zeng, M Li, T Zou, X Chen, Q Li, Y Li, L Ge… - Frontiers in Cell and …, 2021 - frontiersin.org
Increasing evidence demonstrated that PM2. 5 could cross the placenta and fetal blood–
brain barrier, causing neurotoxicity of embryonic development. The retina, an embryologic …

Retinal nerve fiber layer thinning as a novel fingerprint for cardiovascular events: results from the prospective cohorts in UK and China

Y Chen, Y Yuan, S Zhang, S Yang, J Zhang, X Guo… - BMC medicine, 2023 - Springer
Background Retinal structural abnormalities have been found to serve as biomarkers for
cardiovascular disease (CVD). However, the association between retinal nerve fiber layer …

Meandered and muddled: a systematic review on the impact of air pollution on ocular health

N Muruganandam, S Mahalingam… - … Science and Pollution …, 2023 - Springer
Abstract From the years 1970–2023, a systematic overview of the diverse consequences of
particulate matter on eye health and a disease classification according to acute, chronic, and …

Association of long-term ozone air pollution and age-related macular degeneration in older Chinese population

H Jia, Y Guo, H Luo, X Meng, L Zhang, K Yu… - Science of The Total …, 2024 - Elsevier
Background Age-related macular degeneration (AMD) is the leading cause of legal
blindness. It remains unclear whether and to what extent the ambient ozone pollution could …

[HTML][HTML] Impacts of climate change on ocular health: a scoping review

YL Wong, SW Wong, DSJ Ting, A Muralidhar… - The Journal of Climate …, 2024 - Elsevier
Climate change represents a significant global health crisis, characterized by a complex
interplay of environmental shifts and interconnected phenomena. These alterations have …

Airborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis

L Li, C Xing, J Zhou, L Niu, B Luo, M Song, J Niu… - Particle and Fibre …, 2021 - Springer
Background Particulate matter (PM) is strongly linked to human health and has detrimental
effects on the eye. Studies have, however, focused on the ocular surface, with limited …