Protective effects of functional foods against Parkinson's disease: A narrative review on pharmacology, phytochemistry, and molecular mechanisms

M Iranshahy, B Javadi, A Sahebkar - Phytotherapy research, 2022 - Wiley Online Library
Abstract In Persian Medicine (PM), PD (brain‐based tremor) is a known CNS disorder with
several therapeutic and preventive options. In their medical textbooks and pharmacopeias …

An updated literature-based review: phytochemistry, pharmacology and therapeutic promises of Nigella sativa L.

MT Islam, MR Khan, SK Mishra - Oriental Pharmacy and Experimental …, 2019 - Springer
An in depth review on Nigella sativa and its derived constituents has been necessitated
which has been sketched in this paper from the research reports obtained from PubMed and …

Neuroprotective effect of crocin on substantia nigra in MPTP-induced Parkinson's disease model of mice

P Haeri, A Mohammadipour, Z Heidari… - Anatomical science …, 2019 - Springer
Parkinson's disease is caused by damage to substantia nigra dopaminergic neurons.
Factors such as oxidative stress, inflammatory factors, and acetylcholinesterase activity may …

From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders

N Norouzkhani, AG Karimi, N Badami… - Frontiers in …, 2022 - frontiersin.org
Aging is described as an advanced time-related collection of changes that may negatively
affect with the risk of several diseases or death. Aging is a main factor of several age-related …

Oridonin, A natural diterpenoid, protected NGF-differentiated PC12 cells against MPP+-and kainic acid-induced injury

KH Lin, CY Li, YM Hsu, CH Tsai, FJ Tsai… - Food and Chemical …, 2019 - Elsevier
Oridonin (ORI) is a natural diterpenoid presented in some medicinal plants. The effects of
pre-treatments from ORI against MPP+-or kainic acid (KA)-induced damage in nerve growth …

Ethnopharmacological validation of Karkataka Taila-An edible crab Rasayana in rotenone-induced in vitro and in vivo models of Parkinson's disease

NP Deepika, PT Krishnamurthy, MS Varshini… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance 'Karkataka Taila (KT), an ancient Ayurvedic
Rasayana comprising the edible freshwater crab Scylla serrata Forskal flesh, is still used by …

Nigella sativa Oil Reduces LPS‐Induced Microglial Inflammation: An Evaluation on M1/M2 Balance

A Hosseini, V Baradaran Rahimi… - Evidence‐Based …, 2022 - Wiley Online Library
Objectives. The immune system plays a critical defence role against infections, injuries, and
carcinogenic stimuli. As the macrophages of the brain resides in the innate immune system …

Nigella sativa and its nano‐mediated approach toward management of neurodegenerative disorders: A review

CG Gawas, S Mathur, M Wani, H Tabassum - Ibrain, 2023 - Wiley Online Library
Nigella sativa L., also known as black seed or black cumin, is a plant that has been used for
centuries. In the past, this flowering plant was used as a food preservative and medicinal …

Effect of ethanol extract of nigella sativa L seeds and propofol on BDNF protein level as neuroplasticity and neuroprotection of traumatic brain injury in rats

K Kulsum, S Syahrul, K Hasbalah, U Balqis - F1000Research, 2024 - f1000research.com
Background Traumatic brain injury (TBI) is a change in brain function or evidence of brain
pathology caused by external mechanical forces. Brain Derived Neurotrophic Factor (BDNF) …

Apoptosis cell death effect of linoleic acid from nigella sativa on human ovary cancer cells through mitochondrial intrinsic pathway

Y Shokoohinia, G Bahrami, F Taherabadi… - Journal of Reports in …, 2018 - journals.lww.com
In this study, we evaluated the cytotoxic potential of fractions (F1-F5) isolated from hexane
extract of the seeds of N. sativa on human ovarian carcinoma cell line, A2780. F2 showed an …