New perspectives on the treatment of hidradenitis suppurativa

V Amat-Samaranch, E Agut-Busquet… - … in Chronic Disease, 2021 - journals.sagepub.com
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by the
presence of painful nodules, abscesses, chronically draining fistulas, and scarring in …

New and emerging targeted therapies for hidradenitis suppurativa

A Markota Čagalj, B Marinović… - International journal of …, 2022 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease deriving
from the hair follicles. The formation of inflammatory nodules, abscesses, fistulas, and sinus …

Biologics for hidradenitis suppurativa: evolution of the treatment paradigm

CA Maronese, C Moltrasio, G Genovese… - Expert Review of …, 2024 - Taylor & Francis
Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …

Target molecules for future hidradenitis suppurativa treatment

CC Zouboulis, JW Frew… - Experimental …, 2021 - Wiley Online Library
The registration of the tumour necrosis factor‐α inhibitor adalimumab in 2015 was a major
step forward in the treatment of hidradenitis suppurativa/acne inversa (HS). However, it soon …

Clinical implementation of biologics and small molecules in the treatment of hidradenitis suppurativa

P Aarts, K Dudink, ARJV Vossen, KR van Straalen… - Drugs, 2021 - Springer
Hidradenitis suppurativa (HS) is a chronic, recurrent, auto-inflammatory skin disease
originating from the hair follicles. The typical inflammatory nodules, abscesses, and draining …

Immunomodulatory drugs in the treatment of hidradenitis Suppurativa—possibilities and limitations

Z Świerczewska, M Lewandowski… - International Journal of …, 2022 - mdpi.com
Hidradenitis suppurativa, also known as acne inversa, is a chronic, progressive, debilitating,
recurrent inflammatory skin disease characterized by the occurrence of very severe …

Insights into the Pathogenesis of HS and Therapeutical Approaches

E Rosi, MT Fastame, I Scandagli, A Di Cesare… - Biomedicines, 2021 - mdpi.com
Hidradenitis suppurativa (HS) is a debilitating, chronic,(auto) inflammatory disease primarily
affecting apocrine gland-rich areas of the body. Although pathogenic mechanisms …

New treatment of pyoderma gangrenosum and hidradenitis suppurativa: A review

K Yamanaka - The Journal of Dermatology, 2024 - Wiley Online Library
Pyoderma gangrenosum (PG) and hidradenitis suppurativa (HS) are stubborn inflammatory
skin diseases categorized as neutrophilic hypodermal dermatoses. These conditions exhibit …

Evolving utility of apremilast in dermatological disorders for off‐label indications

H Mehta, A Sharma, S Dogra - Clinical and Experimental …, 2022 - academic.oup.com
Apremilast, a small molecule that acts by inhibition of the phosphodiesterase‐4 enzyme, has
been approved by the US Food and Drug Administration for the management of psoriatic …

[HTML][HTML] Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology

E Carmona-Rocha, L Rusiñol, L Puig - Pharmaceutics, 2025 - pmc.ncbi.nlm.nih.gov
Phosphodiesterase-4 (PDE4) is involved in the synthesis of inflammatory cytokines that
mediate several chronic inflammatory disorders, including psoriasis and atopic dermatitis. In …