The ability to genetically manipulate a pathogen is fundamental to discovering factors
governing host–pathogen interactions at the molecular level and is critical for devising …

Type III secretion systems (T3SSs) are utilized by Gram-negative pathogens to enhance
their pathogenesis. This secretion system is associated with the delivery of effectors through …

All Chlamydia species are obligate intracellular bacteria that undergo a unique biphasic
developmental cycle strictly in the lumen of a membrane bound compartment, the inclusion …

Chlamydia trachomatis is a strict intracellular human pathogen. It is the main bacterial cause
of sexually transmitted infections and the etiologic agent of trachoma, which is the leading …

Highlights•Chlamydia infections have damaging consequences on female reproductive
health.•Diverse model systems are required to understand Chlamydia-host …

Chlamydia trachomatis, one species of Chlamydia spp., has the greatest impact on human
health and is the main cause of bacterial sexually transmitted diseases and preventable …

Chlamydia bacteria are obligate intracellular organisms with a phylum-defining biphasic
developmental cycle that is intrinsically linked to its ability to cause disease. The progression …

Background: Chlamydia trachomatis is a prolific human pathogen that can cause serious
long-term conditions if left untreated. Recent developments in Chlamydia genetics have …

The genus Chlamydia consists of diverse, obligate intracellular bacteria that infect various
animals, including humans. Although chlamydial species share many aspects of the typical …

Chlamydia trachomatis is an obligate intracellular pathogen that replicates in a host-derived
vacuole termed the inclusion. Central to pathogenesis is a type III secretion system that …