[HTML][HTML] Oxidative stress in the eye and its role in the pathophysiology of ocular diseases

EW Böhm, F Buonfiglio, AM Voigt, P Bachmann, T Safi… - Redox Biology, 2023 - Elsevier
Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Recent advances in lignin antioxidant: Antioxidant mechanism, evaluation methods, influence factors and various applications

K Li, W Zhong, P Li, J Ren, K Jiang, W Wu - International Journal of …, 2023 - Elsevier
Lignin, a by-product of processing lignocellulosic materials, has a polyphenolic structure
and can be used as an antioxidant directly or synergistically with synthetic types of …

Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Cellular and molecular mechanisms in oxidative stress-related diseases

A Remigante, R Morabito - International Journal of Molecular Sciences, 2022 - mdpi.com
The redox equilibrium is important in preserving the correct functionality of vital cellular
functions. Oxidative stress occurs in both nucleated and non-nucleated cells, and is defined …

Reactive X (where X= O, N, S, C, Cl, Br, and I) species nanomedicine

K Wang, W Mao, X Song, M Chen, W Feng… - Chemical Society …, 2023 - pubs.rsc.org
Reactive oxygen, nitrogen, sulfur, carbonyl, chlorine, bromine, and iodine species (RXS,
where X= O, N, S, C, Cl, Br, and I) have important roles in various normal physiological …

Endogenous and exogenous regulation of redox homeostasis in retinal pigment epithelium cells: An updated antioxidant perspective

Y Markitantova, V Simirskii - International Journal of Molecular Sciences, 2023 - mdpi.com
The retinal pigment epithelium (RPE) performs a range of necessary functions within the
neural layers of the retina and helps ensure vision. The regulation of pro-oxidative and …

Immunomodulatory and antioxidant drugs in glaucoma treatment

F Buonfiglio, N Pfeiffer, A Gericke - Pharmaceuticals, 2023 - mdpi.com
Glaucoma, a group of diseases characterized by progressive retinal ganglion cell loss,
cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of …

Natural antioxidant activities of plants in preventing cataractogenesis

E Imelda, R Idroes, K Khairan, RR Lubis, AH Abas… - Antioxidants, 2022 - mdpi.com
A cataract is a condition that causes 17 million people to experience blindness and is the
most significant cause of vision loss, around 47.9%. The formation of cataracts is linked to …

[HTML][HTML] Molecular docking analysis and in vivo assessment of zinc oxide nanoparticle toxicity in zebrafish larvae

V Aliko, L Vasjari, ES Istifli, G Gjonaj, F Impellitteri… - Aquatic Toxicology, 2024 - Elsevier
The zinc oxide nanoparticles (ZnO-NPs) being widely employed in several industries and
consumer products, are raising concerns about their safety on aquatic biota and human …

Potential properties of natural nutraceuticals and antioxidants in age-related eye disorders

J Maiuolo, RM Bulotta, F Oppedisano, F Bosco… - Life, 2022 - mdpi.com
Eye health is crucial, and the onset of diseases can reduce vision and affect the quality of life
of patients. The main causes of progressive and irreversible vision loss include various …