Sex steroid hormones matter for learning and memory: estrogenic regulation of hippocampal function in male and female rodents

KM Frick, J Kim, JJ Tuscher, AM Fortress - Learning & Memory, 2015 - learnmem.cshlp.org
Ample evidence has demonstrated that sex steroid hormones, such as the potent estrogen
17β-estradiol (E2), affect hippocampal morphology, plasticity, and memory in male and …

Estrogen therapy and cognition: a review of the cholinergic hypothesis

RB Gibbs - Endocrine reviews, 2010 - academic.oup.com
The pros and cons of estrogen therapy for use in postmenopausal women continue to be a
major topic of debate in women's health. Much of this debate focuses on the potential …

Exploratory rearing: a context-and stress-sensitive behavior recorded in the open-field test

O Sturman, PL Germain, J Bohacek - Stress, 2018 - Taylor & Francis
Stressful experiences are linked to anxiety disorders in humans. Similar effects are observed
in rodent models, where anxiety is often measured in classic conflict tests such as the open …

Regulation of object recognition and object placement by ovarian sex steroid hormones

JJ Tuscher, AM Fortress, J Kim, KM Frick - Behavioural brain research, 2015 - Elsevier
The ovarian hormones 17β-estradiol (E 2) and progesterone (P 4) are potent modulators of
hippocampal memory formation. Both hormones have been demonstrated to enhance …

Estrogens and age-related memory decline in rodents: what have we learned and where do we go from here?

KM Frick - Hormones and behavior, 2009 - Elsevier
The question of whether ovarian hormone therapy can prevent or reduce age-related
memory decline in menopausal women has been the subject of much recent debate …

Acute estrogen treatment facilitates recognition memory consolidation and alters monoamine levels in memory-related brain areas

T Inagaki, C Gautreaux, V Luine - Hormones and behavior, 2010 - Elsevier
Acute effects of estrogens on mnemonic processes were examined at the behavioral and
neurochemical levels. 17β-estradiol and 17α-estradiol influences on memory consolidation …

Surgical menopause and estrogen therapy modulate the gut microbiota, obesity markers, and spatial memory in rats

L Zeibich, SV Koebele, VE Bernaud, ZE Ilhan… - Frontiers in Cellular …, 2021 - frontiersin.org
Menopause in human females and subsequent ovarian hormone deficiency, particularly
concerning 17β-estradiol (E2), increase the risk for metabolic dysfunctions associated with …

Sex steroids and cognitive function

VN Luine - Journal of neuroendocrinology, 2008 - Wiley Online Library
Gonadal hormones, most notably oestradiol, enhance some aspects of cognitive function in
animal and human models. However, the demonstrated effects are often not large and …

Sex differences and phase of light cycle modify chronic stress effects on anxiety and depressive-like behavior

TN Huynh, AM Krigbaum, JJ Hanna… - Behavioural brain …, 2011 - Elsevier
The experiment examined whether sex differences and the phase of the light cycle modified
how chronic restraint stress influenced anxiety and depressive-like behavior. Rats were …

[HTML][HTML] The effects of estrogens on spatial learning and memory in female rodents–A systematic review and meta-analysis

J Lymer, H Bergman, S Yang, R Mallick… - Hormones and …, 2024 - Elsevier
Estrogens have inconsistent effects on learning and memory in both the clinical and
preclinical literature. Preclinical literature has the advantage of investigating an array of …