Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

Excitotoxicity is classically defined as the neuronal damage caused by the excessive
release of glutamate, and subsequent activation of excitatory plasma membrane receptors …

Damage-associated molecular patterns (DAMPs) trigger sterile inflammation after tissue
injury, but the mechanisms underlying the resolution of inflammation remain unclear. In this …

Post-ischemic inflammation is an essential step in the progression of brain ischemia-
reperfusion injury. However, the mechanism that activates infiltrating macrophages in the …

This review provides a summary of the protein and RNA biomarkers that have been studied
for the diagnosis and assessment of ischemic stroke. Many of the biomarkers identified …

Ischemic stroke (IS) is a multifactorial and heterogeneous neurological disorder with high
rate of death and long-term impairment. Despite years of studies, there are still no stroke …

Stroke remains a leading cause of death and disability, with limited therapeutic options and
suboptimal tools for diagnosis and prognosis. High throughput technologies such as …

Cerebral inflammation is a promising therapeutic target for ischaemic stroke. After ischaemic
stroke, inflammatogenic self-molecules, which originate from damaged brain tissue due to …

Post‐ischemic inflammation is an essential step in the progression of ischemic stroke. This
review focuses on the function of infiltrating immune cells, macrophages, and T cells, in …

The sterile inflammation caused by damage-associated molecular patterns (DAMPs)
worsens the prognosis following primary injury such as ischemic stroke. However, there are …