Therapeutic potential of amino acids in inflammatory bowel disease

Y Liu, X Wang, CAA Hu - Nutrients, 2017 - mdpi.com
Inflammatory bowel disease (IBD), which includes both ulcerative colitis and Crohn's
disease, is a chronic relapsing inflammation of the gastrointestinal tract, and is difficult to …

Roles of dietary amino acids and their metabolites in pathogenesis of inflammatory bowel disease

X Bao, Z Feng, J Yao, T Li, Y Yin - Mediators of inflammation, 2017 - Wiley Online Library
Inflammatory Bowel Disease (IBD) is a kind of chronic inflammation, which has increasing
incidence and prevalence in recent years. IBD mainly divides into Crohn's disease (CD) and …

Association of fructo-oligosaccharides and arginine improves severity of mucositis and modulate the intestinal microbiota

MER Andrade, LM Trindade, PCL Leocádio… - Probiotics and …, 2023 - Springer
Mucositis is defined as inflammatory and ulcerative lesions along of the gastrointestinal tract
that leads to the imbalance of the intestinal microbiota. The use of compounds with action on …

High-Payload chitosan microparticles for the colonic delivery of quercetin: Development and in-vivo evaluation in a rabbit colitis model

AM Helmy, M Elsabahy, M Abd-Elkareem… - Journal of Drug Delivery …, 2020 - Elsevier
Quercetin, a natural flavonoid has high potential for management of inflammatory bowel
diseases (IBD). However, its onset of action is delayed when administered systemically and …

Aminoguanidine inhibits IL‑1β‑induced protein expression of iNOS and COX‑2 by blocking the NF‑κB signaling pathway in rat articular chondrocytes

Y Ma, X Song, T Ma, Y Li, H Bai… - Experimental and …, 2020 - spandidos-publications.com
Osteoarthritis is a chronic joint disease which has a serious impact on the health and quality
of life of affected humans and animals. As an inhibitor of inducible nitric oxide synthase …

An inulin-type fructan CP-A from Codonopsis pilosula alleviates TNBS-induced ulcerative colitis based on serum-untargeted metabolomics

J Zhou, J Wang, D Li, Z Zhang… - American Journal …, 2024 - journals.physiology.org
Ulcerative colitis (UC) is an inflammatory disease with abdominal pain, diarrhea, and bloody
stool as the main symptoms. Several studies have confirmed that polysaccharides are …

Effects of Aqueous and Methanolic Extracts of Stem Bark of Alstonia boonei De Wild. (Apocynaceae) on Dextran Sodium Sulfate‐Induced Ulcerative Colitis in Wistar …

CF Adjouzem, A Gilbert, M Mbiantcha… - Evidence‐Based …, 2020 - Wiley Online Library
Among the most exploited species in Cameroon, Alstonia boonei is widely used in African
medicine for the relief of several pathologies including gastrointestinal disorders. This study …

Development and in vivo evaluation of chitosan beads for the colonic delivery of azathioprine for treatment of inflammatory bowel disease

AM Helmy, M Elsabahy, GM Soliman… - European Journal of …, 2017 - Elsevier
Azathioprine is a highly efficient immunosuppressant drug used for treatment of
inflammatory bowel disease (IBD). Systemic administration of azathioprine results in …

Arginine supplementation reduces colonic injury, inflammation and oxidative stress of DSS-induced colitis in mice

MER Andrade, PAV de Barros… - Journal of Functional …, 2019 - Elsevier
This study evaluated the mechanisms action of arginine in experimental model of ulcerative
colitis. C57BL/6 mice were randomized into 4 groups: Control group (C): standard diet; …

Gastro‐protective effect of l‐arginine against nitric oxide deficiency‐related mucosal injury induced by indomethacin: Does age matter?

GH Heeba, MA Morsy, ME Mahmoud… - … of Biochemical and …, 2023 - Wiley Online Library
Gastric ulcer is a common disease with increased prevalence in the aged population. Aged
gastric mucosa has increased susceptibility to injury along with nonsteroidal anti …