The addition of clopidogrel to aspirin treatment reduces ischemic events in a wide range of
patients with cardiovascular disease. However, recurrent ischemic event occurrence during …

Studies focused on patient responsiveness to antiplatelet therapies, particularly aspirin and
clopidogrel, have increased in recent years. However, the relations of in vivo platelet …

The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …

Light transmission aggregometry (LTA), which was independently developed in 1962 by
Born 1 and O'Brien 2, is considered the gold standard for testing platelet function, because it …

The guideline writing group was selected to be representative of UK‐based medical experts.
MEDLINE was systematically searched for publications in English up to the Summer of 2010 …

Platelet function testing is important for the diagnostic evaluation of common and rare
bleeding disorders. Our study goals were to promote best practices and reduce unnecessary …

Summary Background Ticagrelor, a P2Y 12 antagonist, is an antiplatelet agent approved for
the treatment of acute coronary syndromes; it also inhibits adenosine uptake by erythrocytes …

Background: Light transmission aggregometry (LTA) is the most common method used in
clinical and research laboratories to assess platelet function. However, the method has …

Light transmission aggregometry (LTA) is the gold standard for the study of patients with
defects of platelet function. Use of LTA in clinical practice for predicting the risk of thrombosis …

Samples for hemostasis testing drawn into sodium citrate anticoagulant are vulnerable to the
effects of preanalytical variables associated with sample processing, transportation, and …