Use of genetically modified lactic acid bacteria and bifidobacteria as live delivery vectors for human and animal health

R Levit, NG Cortes-Perez, A de Moreno de Leblanc… - Gut …, 2022 - Taylor & Francis
There is now strong evidence to support the interest in using lactic acid bacteria (LAB) in
particular, strains of lactococci and lactobacilli, as well as bifidobacteria, for the development …

[HTML][HTML] Transgenic dry eye mouse models: Powerful tools to study dry eye disease

DY Qin, LX Wang, YP Deng - International Journal of …, 2022 - ncbi.nlm.nih.gov
Dry eye disease (DED) is one of the most common chronic multifactorial ocular surface
diseases with high prevalence and complex pathogenesis. DED results in several ocular …

Treatment with a Lactococcus lactis that chromosomally express E. coli cfaI mitigates salivary flow loss in a Sjögren's syndrome-like disease

A Akgul, CF Freguia, M Maddaloni, C Hoffman… - Scientific Reports, 2023 - nature.com
Sjögren's Syndrome (SjS) results in loss of salivary and lacrimal gland excretion due to an
autoimmune attack on these secretory glands. Conventional SjS treatments address the …

Regulatory T cells: a new therapeutic link for Sjögren syndrome?

B Ming, Y Zhu, J Zhong, L Dong - Rheumatology, 2023 - academic.oup.com
Great advancements have been made in understanding the pathogenesis of SS, but there
remain unmet needs for effective and targeted treatments. Glandular and extraglandular …

[HTML][HTML] Sjögren's Syndrome Treatments in the Microbiome Era

CF Freguia, DW Pascual, GR Fanger - Advances in geriatric …, 2023 - ncbi.nlm.nih.gov
Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by inflammatory
cell infiltration of the salivary and lacrimal glands, resulting in acinar epithelial cell atrophy …

EXPRESS: Screening for Presence of Primary Sjogren's Syndrome in Patients with Autoimmune Thyroid Diseases

M Elgebaly, K Shalaby, H Elserougy… - Journal of …, 2024 - journals.sagepub.com
Autoimmune thyroid disorders (AITD) are the most common autoimmune human disorders
as thyroid gland is a main target for autoimmunity. The association between rheumatologic …

Gut Microbiota and Other Factors Associated With Increased Regulatory T Cells in Hiv-exposed Uninfected Infants

M Johnson, SK Lazarus, AE Bennett… - Research …, 2024 - ncbi.nlm.nih.gov
HIV-exposed uninfected infants (HEU) have higher infectious morbidity than HIV-unexposed
infants (HUU). HEU have multiple immune defects of unknown origin. We hypothesized that …