Self-assembling peptide EAK16 and RADA16 nanofiber scaffold hydrogel

F Gelain, Z Luo, S Zhang - Chemical reviews, 2020 - ACS Publications
Short peptides are ubiquitous in nature. They are found as hormones, pheromones,
antibacterial and antifungal agents in innate immunity systems, toxins, and pesticides. But …

Designed peptide amphiphiles as scaffolds for tissue engineering

W Sun, DA Gregory, X Zhao - Advances in Colloid and Interface Science, 2023 - Elsevier
Peptide amphiphiles (PAs) are peptide-based molecules that contain a peptide sequence as
a head group covalently conjugated to a hydrophobic segment, such as lipid tails. They can …

Functional self-assembling peptide nanofiber hydrogels designed for nerve degeneration

Y Sun, W Li, X Wu, N Zhang, Y Zhang… - … applied materials & …, 2016 - ACS Publications
Self-assembling peptide (SAP) RADA16-I (Ac-(RADA) 4-CONH2) has been suffering from a
main drawback associated with low pH, which damages cells and host tissues upon direct …

Nanoparticle transport across the blood brain barrier

AM Grabrucker, B Ruozi, D Belletti, F Pederzoli… - Tissue …, 2016 - Taylor & Francis
While the role of the blood-brain barrier (BBB) is increasingly recognized in the
(development of treatments targeting neurodegenerative disorders, to date, few strategies …

Self-assembling peptides as vectors for local drug delivery and tissue engineering applications

C Karavasili, DG Fatouros - Advanced drug delivery reviews, 2021 - Elsevier
Molecular self-assembly has forged a new era in the development of advanced biomaterials
for local drug delivery and tissue engineering applications. Given their innate …

Peptidic biomaterials: from self-assembling to regenerative medicine

R Pugliese, F Gelain - Trends in biotechnology, 2017 - cell.com
Peptidic biomaterials represent a particularly exciting topic in regenerative medicine.
Peptidic scaffolds can be specifically designed for biomimetic customization for targeted …

Vascularization of self-assembled peptide scaffolds for spinal cord injury repair

KA Tran, PP Partyka, Y Jin, J Bouyer, I Fischer… - Acta biomaterialia, 2020 - Elsevier
The disruption of the blood-spinal cord barrier (BSCB) following spinal cord injury
contributes to inflammation and glial scarring that inhibits axon growth and diminishes the …

A hyaluronic acid/silk fibroin/poly-dopamine-coated biomimetic hydrogel scaffold with incorporated neurotrophin-3 for spinal cord injury repair

Q Sha, Y Wang, Z Zhu, H Wang, H Qiu, W Niu, X Li… - Acta Biomaterialia, 2023 - Elsevier
Bio-factor stimulation is essential for axonal regeneration in the central nervous system.
Thus, persistent and efficient factor delivery in the local microenvironment is an ideal …

Short peptide nanofiber biomaterials ameliorate local hemostatic capacity of surgical materials and intraoperative hemostatic applications in clinics

Z Yang, L Chen, J Liu, H Zhuang, W Lin… - Advanced …, 2023 - Wiley Online Library
Short designer self‐assembling peptide (dSAP) biomaterials are a new addition to the
hemostat group. It may provide a diverse and robust toolbox for surgeons to integrate wound …

Peptide‐based supramolecular therapeutics for fighting major diseases

Z Wang, H Luo, H Wang, M Xiao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …