A comprehensive comparative review of sequence-based predictors of DNA-and RNA-binding residues

J Yan, S Friedrich, L Kurgan - Briefings in bioinformatics, 2016 - academic.oup.com
Motivated by the pressing need to characterize protein–DNA and protein–RNA interactions
on large scale, we review a comprehensive set of 30 computational methods for high …

Computational tools to study RNA-protein complexes

S Bheemireddy, S Sandhya, N Srinivasan… - Frontiers in molecular …, 2022 - frontiersin.org
RNA is the key player in many cellular processes such as signal transduction, replication,
transport, cell division, transcription, and translation. These diverse functions are …

Deep4mC: systematic assessment and computational prediction for DNA N4-methylcytosine sites by deep learning

H Xu, P Jia, Z Zhao - Briefings in bioinformatics, 2021 - academic.oup.com
Abstract DNA N4-methylcytosine (4mC) modification represents a novel epigenetic
regulation. It involves in various cellular processes, including DNA replication, cell cycle and …

[HTML][HTML] In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1

A Chaudhari, M Chaudhari, S Mahera, Z Saiyed… - Informatics in Medicine …, 2021 - Elsevier
Novel severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has claimed more
than 3.3 million lives worldwide and still counting. As per the GISAID database, the …

A boosting approach for prediction of protein-RNA binding residues

Y Tang, D Liu, Z Wang, T Wen, L Deng - BMC bioinformatics, 2017 - Springer
Background RNA binding proteins play important roles in post-transcriptional RNA
processing and transcriptional regulation. Distinguishing the RNA-binding residues in …

DFpin: Deep learning–based protein-binding site prediction with feature-based non-redundancy from RNA level

X Zhao, Y Zhang, X Du - Computers in biology and medicine, 2022 - Elsevier
Highlights•This paper identifies the protein interaction nucleotide sites with the
characteristics of the RNA sequence.•This paper removes redundant data based on the …

Comprehensive survey and comparative assessment of RNA-binding residue predictions with analysis by RNA type

K Wang, G Hu, Z Wu, H Su, J Yang… - International journal of …, 2020 - mdpi.com
With close to 30 sequence-based predictors of RNA-binding residues (RBRs), this
comparative survey aims to help with understanding and selection of the appropriate tools …

Genome-wide functional annotation of human protein-coding splice variants using multiple instance learning

B Panwar, R Menon, R Eksi, HD Li… - Journal of proteome …, 2016 - ACS Publications
The vast majority of human multiexon genes undergo alternative splicing and produce a
variety of splice variant transcripts and proteins, which can perform different functions. These …

RPI-Bind: a structure-based method for accurate identification of RNA-protein binding sites

J Luo, L Liu, S Venkateswaran, Q Song, X Zhou - Scientific reports, 2017 - nature.com
RNA and protein interactions play crucial roles in multiple biological processes, while these
interactions are significantly influenced by the structures and sequences of protein and RNA …

Efficient mapping of RNA‐binding residues in RNA‐binding proteins using local sequence features of binding site residues in protein‐RNA complexes

A Agarwal, S Kant, RP Bahadur - Proteins: Structure, Function …, 2023 - Wiley Online Library
Protein‐RNA interactions play vital roles in plethora of biological processes such as
regulation of gene expression, protein synthesis, mRNA processing and biogenesis …