Ageing is a natural ontogenetic phenomenon that entails a decrease in the adaptive
capacity of the organism, as a result of which the body becomes less adaptable to stressful …

Abstract Aim Dietary nitrate (NO3−) supplementation increases nitric oxide bioavailability
and can enhance exercise performance. We investigated the distribution and metabolic fate …

Recent studies have identified skeletal muscle as a tissue compartment where nitrate and
nitrite can be stored and utilized to potentially maintain nitric oxide (NO) homeostasis. Given …

The activity and quantity of mitochondrial proteins and the mitochondrial volume density
(MitoVD) are higher in trained muscles; however, the underlying mechanisms remain …

Background Skeletal muscles are postulated to be a potent regulator of systemic nitric oxide
homeostasis. In this study, we aimed to evaluate the impact of physical training on the heart …

Myoglobin (Mb) plays an important role at rest and during exercise as a reservoir of oxygen
and has been suggested to regulate NO• bioavailability under hypoxic/acidic conditions …

Introduction The effect of androgens on the cardiovascular system in humans is ambiguous.
Moreover, still little is known about the effects of the most potent androgen …

The use of nitrate (NO3-) as a dietary supplement to augment health and improve exercise
performance has gained considerable attention in the last decade, with substantial evidence …

Впливу надлишкового надходження фтору на організм зазнають мільйони людей.
Вплив фторидів на активацію чи інгібіцію редокс-чутливих транскрипційних факторів …

Millions of people are affected by excessive fluoride intake. The effect of fluorides on the
activation or inhibition of redox-sensitive transcription factors remains poorly understood …