The centromere represents a single region in most eukaryotic chromosomes. However,
several plant and animal lineages assemble holocentromeres along the entire chromosome …

Centromeres play a key role in the maintenance of genome stability to prevent
carcinogenesis and diseases. They are specialized chromosome loci essential to ensure …

Centromeres are critical structures involved in chromosome segregation, maintaining
genomic stability, and facilitating the accurate transmission of genetic information. They are …

The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

The kinetochore complex, an important protein assembly situated on the centromere, plays a
pivotal role in chromosome segregation during cell division. Like in animals and fungi, the …

Plant genetic engineering and transgenic technology are powerful ways to study the function
of genes and improve crop yield and quality in the past few years. However, only a few …

Centromeres are known to cluster around nucleoli in Drosophila and mammalian cells, but
the significance of the nucleoli–centromere interaction remains underexplored. To …

The centromere is an essential chromatin domain required for kinetochore recruitment and
chromosome segregation in eukaryotes. To perform this role, centro-chromatin adopts a …

Kinetochores assemble on centromeres via histone H3 variant CENP-A and low levels of
centromere transcripts (cenRNAs). The latter are ensured by the downregulation of RNA …

Objectives This study aims to investigate how human papillomavirus (HPV) affects the key
gene in the biological behaviors of head and neck squamous cell carcinoma (HNSCC) that …