Urotensin II (UII) is an 11 amino acid cyclic peptide originally isolated from the goby fish. The
amino acid sequence of UII is exceptionally conserved across most vertebrate taxa, sharing …

Urotensin II (UII) is a cyclic neuropeptide that was first isolated from the urophysis of teleost
fish on the basis of its ability to contract the hindgut. Subsequently, UII was characterized in …

11beta-Hydroxysteroid dehydrogenases (11beta-HSDs) interconvert active corticosterone
and inert 11-dehydrocorticosterone. In tissue homogenates, 11beta-HSD type 1 (11beta …

Aims Myostatin (Mstn), a member of the transforming growth factors (TGF)‐β family that
regulate skeletal muscle growth, has been identified as a regulator of cardiomyocyte growth …

Hypertension is a well-known risk factor for atherosclerosis, but the molecular mechanisms
that link elevated blood pressure to the progression of atherosclerosis remain unclear …

Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiovascular
disease (CVD). Urotensin II ((U-II)) and its receptor (UTR) are involved in the progression of …

Aim: To study whether urotensin II (UII), a potent vasoconstrictive peptide, is involved in the
development of cardiac hypertrophy and fibrogenesis of rats induced by isoproterenol (ISO) …

Abstract Urotensin II (U-II) is currently the most potent vasoconstrictor identified. This action
is brought about via activation of a G q/11-protein coupled receptor (UT receptor). U-II …

Human urotensin II (U-II), the most potent vasoconstrictor undecapeptide identified to date,
and its receptor (UT) are involved in the pathogenesis of systemic and pulmonary …

Urotensin II is a potent vasoconstrictive peptide that mediates both endothelium-
independent vasoconstriction and endothelium-dependent vasodilatation. Its plasma level …