Gadolinium as an MRI contrast agent

HK Kim, GH Lee, Y Chang - Future Medicinal Chemistry, 2018 - Taylor & Francis
MRI contrast is often enhanced using a contrast agent. Gd3+-complexes are the most widely
used metallic MRI agents, and several types of Gd3+-based contrast agents (GBCAs) have …

Stability of gadolinium-based magnetic resonance imaging contrast agents in human serum at 37 C

T Frenzel, P Lengsfeld, H Schirmer, J Hütter… - Investigative …, 2008 - journals.lww.com
Objectives: Assessment of the complex stability and Gd 3+ dissociation rate of all marketed
gadolinium-based MRI contrast agents (GBCA) in human serum at pH 7.4 and 37 C …

Stem cell–nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy

YH Lai, CY Su, HW Cheng, CY Chu, LB Jeng… - Nature …, 2023 - nature.com
The potential clinical application of gadolinium-neutron capture therapy (Gd-NCT) for
glioblastoma multiforme (GBM) treatment has been compromised by the fast clearance and …

[HTML][HTML] Spatiotemporal tracking of gold nanorods after intranasal administration for brain targeting

S Han, JTW Wang, E Yavuz, A Zam, N Rouatbi… - Journal of Controlled …, 2023 - Elsevier
Intranasal administration is becoming increasingly more attractive as a fast delivery route to
the brain for therapeutics circumventing the blood-brain barrier (BBB). Gold nanorods …

Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics

JL Arias, LH Reddy, M Othman, B Gillet, D Desmaele… - ACS …, 2011 - ACS Publications
This study reports the design of a novel theragnostic nanomedicine which combines (i) the
ability to target a prodrug of gemcitabine to an experimental solid tumor under the influence …

Gadolinium-Doped Carbon Nanodots as Potential Anticancer Tools for Multimodal Image-Guided Photothermal Therapy and Tumor Monitoring

N Mauro, R Cillari, C Gagliardo, MA Utzeri… - ACS Applied Nano …, 2023 - ACS Publications
This study focuses on the synthesis and characterization of gadolinium-doped carbon
nanodots (CDs-Gd) and their potential applications in multimodal imaging and precision …

Encapsulation of Gadolinium Oxide Nanoparticle (Gd2O3) Contrasting Agents in PAMAM Dendrimer Templates for Enhanced Magnetic Resonance Imaging in Vivo

SL Mekuria, TA Debele, HC Tsai - ACS applied materials & …, 2017 - ACS Publications
There has been growing interest in the research of nanomaterials for biomedical
applications in recent decades. Herein, a simple approach to synthesize the G4. 5-Gd2O3 …

In vivo maps of extracellular pH in murine melanoma by CEST–MRI

D Delli Castelli, G Ferrauto, JC Cutrin… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose A novel method based on the use of Yb‐HPDO3A as MRI Para‐CEST agent for in
vivo pH mapping of the tumor region in a melanoma murine model is reported. This method …

One-pot synthesis of gadolinium-doped carbon quantum dots for high-performance multimodal bioimaging

Y Pan, J Yang, Y Fang, J Zheng, R Song… - Journal of Materials …, 2017 - pubs.rsc.org
In this study, an efficient and mild approach is reported for the facile synthesis of a carbon
quantum dot (CQD)-based dual-modal fluorescence (FL)/magnetic resonance (MR) imaging …

Repeated recovery of rare earth elements using a highly selective and thermo‐responsive genetically encoded polypeptide

Z Hussain, S Kim, J Cho, G Sim… - Advanced Functional …, 2022 - Wiley Online Library
Rare earth elements (REEs) have become increasingly important materials owing to their
use in the high‐tech and clean‐energy industries. However, the unpredictable supply …