Low back pain is a highly prevalent, chronic, and costly medical condition predominantly
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …

Intervertebral disc (IVD) degeneration is a major risk factor of low back pain. It is defined by a
progressive loss of the IVD structure and functionality, leading to severe impairments with …

This research investigates the accelerated hydrolytic degradation process of both
anatomically designed bone scaffolds with a pore size gradient and a rectangular shape …

Lower back pain is a medical condition of epidemic proportion, and the degeneration of the
intervertebral disc has been identified as a major contributor. The etiology of intervertebral …

Low back pain is associated with degenerative disc diseases of the spine. Surgical
treatment includes fusion and non-fusion types. The gold standard is fusion surgery, wherein …

Finite element analysis (FEA) is a widely used tool in a variety of industries and research
endeavors. With its application to spine biomechanics, FEA has contributed to a better …

Introduction Pathologic vertebral fractures are a major clinical concern in the management of
cancer patients with metastatic spine disease. These fractures are a direct consequence of …

A comprehensive understanding of multiscale and multiphasic intervertebral disc mechanics
is crucial for designing advanced tissue engineered structures aiming to recapitulate native …

The assessment of risk of vertebral fracture in patients with lytic metastases is challenging,
due to the complexity in modelling the mechanical properties of this heterogeneous material …

Finite element (FE) analyses contribute to a better understanding of the human lumbar
spine's biomechanics and serve as an effective predictive tool. This study aims to present …