Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Successful cloning of monkeys, the first non-human primate species, by somatic cell nuclear
transfer (SCNT) attracted worldwide attention earlier this year. Remarkably, it has taken …

Generation of genetically uniform non-human primates may help to establish animal models
for primate biology and biomedical research. In this study, we have successfully cloned …

High-quality schematic illustrations are fundamental to the publication of scientific
achievements in biomedical research, which are crucial for effectively conveying complex …

Pluripotency can be induced in differentiated murine and human cells by retroviral
transduction of Oct4, Sox2, Klf4, and c-Myc. We have devised a reprogramming strategy in …

In this study, we demonstrate the production of transgenic goats by nuclear transfer of fetal
somatic cells. Donor karyoplasts were obtained from a primary fetal somatic cell line derived …

The resetting of a somatic epigenotype to a totipotential state has been demonstrated by
successful animal cloning, via transplantation of somatic nuclei into enucleated oocytes. We …

Like other mammals, humans inherit mitochondria from the mother only, even though the
sperm contributes nearly one hundred mitochondria to the fertilized egg. In support of the …

Pig cloning will have a marked impact on the optimization of meat production and
xenotransplantation. To clone pigs from differentiated cells, we microinjected the nuclei of …

Mammalian development commences with the totipotent zygote which is capable of
developing into all the specialized cells that make up the adult animal. As development …