Interest in precision diagnostics has been fuelled by the concept that early detection of
cancer would benefit patients; that is, if detected early, more tumours should be resectable …

Abstract IL-9-producing CD4+ T cells have been considered to represent a distinct T helper
cell (TH cell) subset owing to their unique developmental programme in vitro, their …

Purpose Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, with a 5-year
survival of< 10% because of diffuse symptoms leading to late-stage diagnosis. That survival …

Highlights•Review of cross-reactivity in single-plex and multiplex immunoassays.•Analysis of
why cross-reactivity can disproportionally affects multiplex immunoassays.•Review of eight …

Bedaquiline (aka, Sirturo) is an anti-microbial agent, which is approved by the FDA for the
treatment of multi-drug resistant pulmonary tuberculosis (TB). Bedaquiline is a first-in-class …

The concept of antibody microarrays is one of the most versatile approaches within
multiplexed immunoassay technologies. These types of arrays have increasingly become an …

Although IL-9 has potent anti-tumor activity in adoptive cell transfer therapy, some models
suggest that it can promote tumor growth. Here, we show that IL-9 signaling is associated …

Background Allergic contact dermatitis is an inflammatory skin disease that affects a
significant proportion of the population. This disease is caused by an adverse immune …

Abstract Interleukin (IL)-9 belongs to the IL-2Rγc chain family and is a multifunctional
cytokine that can regulate the function of many kinds of cells. It was originally identified as a …

Network analysis is the preferred approach for the detection of subtle but coordinated
changes in expression of an interacting and related set of genes. We introduce a novel …