Recent advances on quinazoline derivatives: A potential bioactive scaffold in medicinal chemistry

R Karan, P Agarwal, M Sinha, N Mahato - ChemEngineering, 2021 - mdpi.com
This paper intended to explore and discover recent therapeutic agents in the area of
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …

Free radical scavengers: An overview on heterocyclic advances and medicinal prospects

K Haider, MR Haider, K Neha, MS Yar - European Journal of Medicinal …, 2020 - Elsevier
In the present scenario, there has been a lot of consideration toward the field of free radical
chemistry. Free radicals responsive oxygen species are produced by different endogenous …

Antioxidant Activities of a New Chemotype of Piper cubeba L. Fruit Essential Oil (Methyleugenol/Eugenol): In Silico Molecular Docking and ADMET Studies

F Alminderej, S Bakari, TI Almundarij, M Snoussi… - Plants, 2020 - mdpi.com
Piper cubeba L. fruit is an important species used in folk medicine for different types of pains
such as rheumatism, chills, flu, colds, muscular aches, and fever. This study examines the …

Effect of monosodium glutamate on serum sex hormones and uterine histology in female rats along with its molecular docking and in-silico toxicity

MAM Abdulghani, SA Alshehade, S Kamran… - Heliyon, 2022 - cell.com
Monosodium glutamate (MSG) is commonly used worldwide as a food flavour enhancer by
the food industry. The current study investigated the in vivo toxic effects of MSG on the uterus …

Preparation, Agricultural Bioactivity Evaluation, Structure–Activity Relationships Estimation, and Molecular Docking of Some Quinazoline Compounds

BRM Hussein, AH Moustafa, A Abdou… - Journal of Agricultural …, 2024 - ACS Publications
Quinazoline compounds have gained significant attention in the fields of agriculture and
chemistry due to their diverse activities. In this study, we focused on a series of quinazoline …

Novel quinazoline–chromene hybrids as anticancer agents: Synthesis, biological activity, molecular docking, dynamics and ADME studies

FS Tokalı, H Şenol, Hİ Yetke… - Archiv der …, 2023 - Wiley Online Library
In this study, new quinazoline–chromene hybrid compounds were synthesized. The
cytotoxic effects on cell viability of the hybrid compounds were tested against A549 human …

Investigation of 4-hydrazinobenzoic acid derivatives for their antioxidant activity: In vitro screening and DFT study

HA Abuelizz, HAA Taie, AH Bakheit, GAE Mostafa… - ACS …, 2021 - ACS Publications
Hydrazinobenzoic acid derivatives with isothiocyanate, benzylidene, and acid anhydride
core units (1–13) were previously synthesized and fully characterized. Targets 1–13 were …

A comprehensive review of recent advances in the biological activities of quinazolines

HAM Gomaa - Chemical Biology & Drug Design, 2022 - Wiley Online Library
Quinazoline heterocycles are critical in the development of medications. Quinazoline
derivatives have been intensively researched, providing a wide range of compounds with …

An overview of triazoloquinazolines: Pharmacological significance and recent developments

HA Abuelizz, R Al-Salahi - Bioorganic Chemistry, 2021 - Elsevier
Nitrogen heterocyclic rings have participated to constitute most of the drugs and several
pharmacologically related compounds. The existence of such hetero atoms/groups in …

Antiviral activity of some benzo [g] quinazolines against coxsackievirus B4: Biological screening and docking study

HA Abuelizz, AH Bakheit, M Marzouk… - Pharmacological …, 2023 - Springer
Abstract Background Serotype coxsackievirus B (CVB) infection has been linked to viral
myocarditis, dilated cardiomyopathy, meningitis, and pancreatitis in children and young …