The measured induction times in droplet-based microfluidic systems are stochastic and are
not described by the deterministic population balances or moment equations commonly …

One of the most crucial parameters in protein crystallization is pH, as it governs the protein's
electrostatic interactions. However, the fundamental role of pH on crystallization still remains …

The crystal nucleation process in solutions plays an important role in both the engineering
processes and the physical science. To seek the truth of nucleation, researchers have …

Number density of insulin crystals versus nucleation time dependences were measured
simultaneously, during the same experiment, at four typical places: in solution bulk, at the …

The principles of the classical nucleation theory (CNT), originating from JW Gibbs, are
presented in this chapter. Then, thermodynamics, critical nucleus size, energy barriers, and …

The main feature of this paper was to recognize struvite crystallization in the metastable
region of supersaturation. Thermodynamic equilibria of struvite were simulated to identify the …

Although half a century has passed since the mapping of the insulin structure, this globular
protein is still currently being investigated. Crystalline drug formulations might replace the …

Nucleation of protein crystals by gold nanoparticles was observed. Lysozyme and ferritin
were used as model proteins. The effect was established with uncoated gold nanoparticles …

Insulin is a human therapeutic protein that has been used to treat diabetes for almost a
century. Its crystallization has been of significant interest since the protein is commonly …

Experimental and theoretical investigations on protein crystal nucleation are reviewed.
Various experimental applications of the classical principle, which requires separation of the …