Myocardial energetics in heart failure

A Nickel, J Löffler, C Maack - Basic research in cardiology, 2013 - Springer
It has become common sense that the failing heart is an “engine out of fuel”. However,
undisputable evidence that, indeed, the failing heart is limited by insufficient ATP supply is …

β-Blockers in hypertension, diabetes, heart failure and acute myocardial infarction: a review of the literature

JJ DiNicolantonio, H Fares, AK Niazi, S Chatterjee… - Open …, 2015 - openheart.bmj.com
β-Blockers (BBs) are an essential class of cardiovascular medications for reducing morbidity
and mortality in patients with heart failure (HF). However, a large body of data indicates that …

Soluble concentrations of the interleukin receptor family member ST2 and β-blocker therapy in chronic heart failure

HK Gaggin, S Motiwala, A Bhardwaj… - Circulation: Heart …, 2013 - Am Heart Assoc
Background—Concentrations of soluble (s) ST2 predict prognosis in heart failure. We
recently found changing doses of β-blocker (BB) may affect sST2 concentrations. It remains …

Arrhythmogenic Remodeling of β2 Versus β1 Adrenergic Signaling in the Human Failing Heart

D Lang, K Holzem, C Kang, M Xiao… - Circulation …, 2015 - Am Heart Assoc
Background—Arrhythmia is the major cause of death in patients with heart failure, for which
β-adrenergic receptor blockers are a mainstay therapy. But the role of β-adrenergic …

[HTML][HTML] Contemporary use of β-blockers: clinical relevance of subclassification

L Poirier, SW Tobe - Canadian Journal of Cardiology, 2014 - Elsevier
Abstract β-Adrenergic receptor blockers or β-blockers represent one of the oldest classes of
cardiovascular agents and have been considered a cornerstone therapy for hypertension …

Scar border zone mass and presence of border zone channels assessed with cardiac magnetic resonance imaging are associated with ventricular arrhythmia in …

AF Thomsen, L Bertelsen, C Jøns, R Jabbari… - Europace, 2023 - academic.oup.com
Aims Late gadolinium enhancement cardiac magnetic resonance (CMR) permits
characterization of left ventricular ischaemic scars. We aimed to evaluate if scar core mass …

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure

C Crocini, R Coppini, C Ferrantini… - Proceedings of the …, 2014 - National Acad Sciences
Action potentials (APs), via the transverse axial tubular system (TATS), synchronously trigger
uniform Ca2+ release throughout the cardiomyocyte. In heart failure (HF), TATS structural …

Association between frequency of atrial and ventricular ectopic beats and biventricular pacing percentage and outcomes in patients with cardiac resynchronization …

MH Ruwald, S Mittal, AC Ruwald, MK Aktas… - Journal of the American …, 2014 - jacc.org
Background: A high percentage of biventricular pacing is required for optimal outcome in
patients treated with cardiac resynchronization therapy (CRT), but the influence of ectopic …

Left bundle branch block-induced left ventricular remodeling and its potential for reverse remodeling

E Sze, JP Daubert - Journal of Interventional Cardiac Electrophysiology, 2018 - Springer
With the emergence of cardiac resynchronization therapy (CRT) as a powerful tool to
reverse left ventricular dysfunction in patients with left bundle branch block (LBBB), there is …

Hypertension and ethnicity

A Bennett, P Parto, SR Krim - Current Opinion in Cardiology, 2016 - journals.lww.com
Despite recent progress, racial disparities in awareness and treatment of HTN continue to
exist. To reduce this important gap, future research should focus on epidemiologic, genetic …