Cytokine storm syndrome

RQ Cron, G Goyal, WW Chatham - Annual Review of Medicine, 2023 - annualreviews.org
Cytokine storm syndrome (CSS), which is frequently fatal, has garnered increased attention
with the ongoing coronavirus pandemic. A variety of hyperinflammatory conditions …

Hemophagocytic lymphohistiocytosis: an update on pathogenesis, diagnosis, and therapy

G Griffin, S Shenoi, GC Hughes - Best Practice & Research Clinical …, 2020 - Elsevier
Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening state of immune
hyperactivation that arises in the setting of genetic mutations and infectious, inflammatory, or …

Lessons to be learnt from real-world studies on immune-related adverse events with checkpoint inhibitors: a clinical perspective from pharmacovigilance

E Raschi, M Gatti, F Gelsomino, A Ardizzoni… - Targeted Oncology, 2020 - Springer
The advent of immune checkpoint inhibitors (ICIs) caused a paradigm shift both in drug
development and clinical practice; however, by virtue of their mechanism of action, the …

Malignancy-associated haemophagocytic lymphohistiocytosis

A Setiadi, A Zoref-Lorenz, CY Lee, MB Jordan… - The Lancet …, 2022 - thelancet.com
Haemophagocytic lymphohistiocytosis (HLH) is an inflammatory syndrome that can occur
with cancer (malignancy-associated HLH) or with immune-activating therapies for cancer …

Hemophagocytic lymphohistiocytosis associated with immunological checkpoint inhibitors: a pharmacovigilance study

L Diaz, B Jauzelon, AC Dillies, C Le Souder… - Journal of Clinical …, 2023 - mdpi.com
Background: Acquired hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially
fatal condition characterized by hyperactivation of macrophages and cytotoxic lymphocytes …

[PDF][PDF] 血液系统肿瘤治疗相关噬血细胞综合征的诊疗进展

刘艺, 郭涛 - 临床血液学杂志, 2022 - whuhzzs.com
专家简介: 郭涛, 华中科技大学同济医学院附属协和医院血液科主任医师, 博士生导师.
担任中国医师协会血液科医师分会委员, 海峡两岸医药卫生交流协会血液病学专业委员会副主任 …

Two-year outcomes and Biomarker Analysis of locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma after Neoadjuvant Chemotherapy and …

X Sun, J Lyu, M Yang, Y Lin, K Wu, K Liu, A Li… - Annals of Surgical …, 2024 - Springer
Background This study reports the 2-year outcomes and biomarker analysis results of
patients with locally advanced gastric and gastroesophageal junction (G/GEJ) …

Inpatient recognition and management of HLH

A Zoref-Lorenz, M Ellis, MB Jordan - Hematology, 2023 - ashpublications.org
Hemophagocytic lymphohistiocytosis (HLH) is one of the life-threatening emergencies that a
hematologist may be called upon to diagnose and manage. It is a hyperinflammatory …

Diagnosis and management of adult malignancy-associated hemophagocytic lymphohistiocytosis

JC Lee, AC Logan - Cancers, 2023 - mdpi.com
Simple Summary Although rare, hemophagocytic lymphohistiocytosis (HLH), a syndrome of
severe, dysregulated inflammation, is associated with poor survival when it occurs in …

[HTML][HTML] Hemophagocytic lymphohistiocytosis secondary to immune checkpoint inhibitor therapy

P Rajapakse, H Andanamala - World Journal of Oncology, 2022 - ncbi.nlm.nih.gov
Hemophagocytic lymphohistiocytosis (HLH) is a fatal systemic inflammatory syndrome. HLH
has been reported as a rare immune-related adverse event (irAE) in patients receiving …