Quantitative magnetic resonance imaging of brain anatomy and in vivo histology

N Weiskopf, LJ Edwards, G Helms… - Nature Reviews …, 2021 - nature.com
Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis

C Granziera, J Wuerfel, F Barkhof, M Calabrese… - Brain, 2021 - academic.oup.com
Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

[HTML][HTML] Quantitative susceptibility mapping (QSM) as a means to measure brain iron? A post mortem validation study

C Langkammer, F Schweser, N Krebs, A Deistung… - Neuroimage, 2012 - Elsevier
Quantitative susceptibility mapping (QSM) is a novel technique which allows determining the
bulk magnetic susceptibility distribution of tissue in vivo from gradient echo magnetic …

Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline

S Ayton, A Fazlollahi, P Bourgeat, P Raniga, A Ng… - Brain, 2017 - academic.oup.com
Abstract See Derry and Kent (doi: 10.1093/awx167) for a scientific commentary on this
article. The large variance in cognitive deterioration in subjects who test positive for amyloid …

Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes

YJ Bae, JM Kim, CH Sohn, JH Choi, BS Choi, YS Song… - Radiology, 2021 - pubs.rsna.org
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

Quantitative imaging of intrinsic magnetic tissue properties using MRI signal phase: an approach to in vivo brain iron metabolism?

F Schweser, A Deistung, BW Lehr, JR Reichenbach - Neuroimage, 2011 - Elsevier
Quantitative susceptibility mapping (QSM) based on gradient echo (GRE) magnetic
resonance phase data is a novel technique for non-invasive assessment of magnetic tissue …

Toward in vivo histology: a comparison of quantitative susceptibility mapping (QSM) with magnitude-, phase-, and R2⁎-imaging at ultra-high magnetic field strength

A Deistung, A Schäfer, F Schweser, U Biedermann… - Neuroimage, 2013 - Elsevier
Quantitative magnetic susceptibility mapping (QSM) has recently been introduced to provide
a novel quantitative and local MRI contrast. However, the anatomical contrast represented …

Iron, myelin, and the brain: neuroimaging meets neurobiology

HE Möller, L Bossoni, JR Connor, RR Crichton… - Trends in …, 2019 - cell.com
Although iron is crucial for neuronal functioning, many aspects of cerebral iron biology await
clarification. The ability to quantify specific iron forms in the living brain would open new …

Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions

UW Kaunzner, Y Kang, S Zhang, E Morris, Y Yao… - Brain, 2019 - academic.oup.com
Chronic active multiple sclerosis lesions, characterized by a hyperintense rim of iron-
enriched, activated microglia and macrophages, have been linked to greater tissue damage …

MRI in traumatic spinal cord injury: from clinical assessment to neuroimaging biomarkers

P Freund, M Seif, N Weiskopf, K Friston… - The Lancet …, 2019 - thelancet.com
Traumatic spinal cord injury occurs when an external physical impact damages the spinal
cord and leads to permanent neurological dysfunction and disability, and it is associated …