Clefts of the lip and palate are generally divided into two groups, isolated cleft palate and
cleft lip with or without cleft palate, representing a heterogeneous group of disorders …

Clefts of the lip and/or palate (CL/P) are among the most common birth defects worldwide.
The majority are non-syndromic where CL/P occurs in isolation of other phenotypes. Where …

Clefts of the lip and palate (CLP), the major causes of congenital facial malformation
globally, result from failure of fusion of the facial processes during embryogenesis. With a …

Compared with the embryonic development of other organs, development of the secondary
palate is seemingly simple. However, each step of palatogenesis, from initiation until …

Abstract Scanning Electron Microscope (SEM) is a powerful research tool, but since it
requires high vacuum conditions, the wet materials and biological samples must undergo a …

The rapid proliferative expansion and complex morphogenetic events that coordinate the
development of the face underpin the sensitivity of this structure to genetic and …

In mammals, adhesion and fusion of the palatal shelves are essential mechanisms during
the development of the secondary palate; failure of these processes leads to the congenital …

Craniofacial development is a multistep and intricate process initially involving a number of
inductive interactions that control neural and neural crest development, which are followed …

Palate fusion is a complex process that involves the coordination of a series of cellular
changes including cell death and epithelial to mesenchymal transition (EMT). Since …

Formation of the palate, the organ that separates the oral cavity from the nasal cavity, is a
developmental process characteristic to embryos of higher vertebrates. Failure in this …