Time-dependent diffusion MRI in cancer: tissue modeling and applications

O Reynaud - Frontiers in Physics, 2017 - frontiersin.org
In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been
recognized as a useful and sensitive surrogate for cell density, paving the way for non …

[HTML][HTML] Gradient waveform design for tensor-valued encoding in diffusion MRI

F Szczepankiewicz, CF Westin, M Nilsson - Journal of Neuroscience …, 2021 - Elsevier
Diffusion encoding along multiple spatial directions per signal acquisition can be described
in terms of a b-tensor. The benefit of tensor-valued diffusion encoding is that it unlocks …

Noninvasive quantification of solid tumor microstructure using VERDICT MRI

E Panagiotaki, S Walker-Samuel, B Siow, SP Johnson… - Cancer research, 2014 - AACR
There is a need for biomarkers that are useful for noninvasive imaging of tumor
pathophysiology and drug efficacy. Through its use of endogenous water, diffusion-weighted …

Microstructural characterization of normal and malignant human prostate tissue with vascular, extracellular, and restricted diffusion for cytometry in tumours magnetic …

E Panagiotaki, RW Chan, N Dikaios… - Investigative …, 2015 - journals.lww.com
Objective The aim of this study was to demonstrate the feasibility of the recently introduced
Vascular, Extracellular, and Restricted Diffusion for Cytometry in Tumours (VERDICT) …

On the origins of chemical exchange saturation transfer (CEST) contrast in tumors at 9.4 T

J Xu, M Zaiss, Z Zu, H Li, J Xie, DF Gochberg… - NMR in …, 2014 - Wiley Online Library
Chemical exchange saturation transfer (CEST) provides an indirect means to detect
exchangeable protons within tissues through their effects on the water signal. Previous …

Characterization of tissue structure at varying length scales using temporal diffusion spectroscopy

JC Gore, J Xu, DC Colvin, TE Yankeelov… - NMR in …, 2010 - Wiley Online Library
The concepts, theoretical behavior and experimental applications of temporal diffusion
spectroscopy are reviewed and illustrated. Temporal diffusion spectra are obtained using …

Time-dependent diffusion MRI for quantitative microstructural mapping of prostate cancer

D Wu, K Jiang, H Li, Z Zhang, R Ba, Y Zhang, YC Hsu… - Radiology, 2022 - pubs.rsna.org
Background Recently developed time-dependent diffusion MRI has potential in
characterizing cellular tissue microstructures; however, its value in imaging prostate cancer …

Probing mouse brain microstructure using oscillating gradient diffusion MRI

M Aggarwal, MV Jones, PA Calabresi… - Magnetic resonance …, 2012 - Wiley Online Library
High resolution diffusion tensor images of the mouse brain were acquired using the pulsed
gradient spin echo sequence and the oscillating gradient spin echo sequence. The …

Diffusion dispersion imaging: Mapping oscillating gradient spin‐echo frequency dependence in the human brain

A Arbabi, J Kai, AR Khan… - Magnetic resonance in …, 2020 - Wiley Online Library
Purpose Oscillating gradient spin‐echo (OGSE) diffusion MRI provides information about the
microstructure of biological tissues by means of the frequency dependence of the apparent …

Oscillating gradient diffusion MRI reveals unique microstructural information in normal and hypoxia‐ischemia injured mouse brains

D Wu, LJ Martin, FJ Northington… - Magnetic resonance in …, 2014 - Wiley Online Library
Purpose We investigated whether oscillating gradient diffusion MRI (dMRI) can provide
information on brain microstructural changes after formaldehyde fixation and after hypoxic …