[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M Ghezzi, S Pescina, C Padula, P Santi… - Journal of Controlled …, 2021 - Elsevier
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Considerations for polymers used in ocular drug delivery

MM Allyn, RH Luo, EB Hellwarth… - Frontiers in …, 2022 - frontiersin.org
Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …

Insights on development aspects of polymeric nanocarriers: the translation from bench to clinic

AK Tewari, SC Upadhyay, M Kumar, K Pathak… - Polymers, 2022 - mdpi.com
Scientists are focusing immense attention on polymeric nanocarriers as a prominent delivery
vehicle for several biomedical applications including diagnosis of diseases, delivery of …

Recent development of polymer nanomicelles in the treatment of eye diseases

R Cai, L Zhang, H Chi - Frontiers in bioengineering and …, 2023 - frontiersin.org
The eye, being one of the most intricate organs in the human body, hosts numerous
anatomical barriers and clearance mechanisms. This highlights the importance of devising a …

Role of polymeric micelles in Ocular Drug Delivery: an overview of decades of Research

Z Binkhathlan, R Ali, AH Alomrani… - Molecular …, 2023 - ACS Publications
Local drug delivery to the eye through conventional means has faced many challenges due
to three essential barriers:(a) the complex structure of the cornea limiting drug absorption,(b) …

Recent advances of ocular drug delivery systems: prominence of ocular implants for chronic eye diseases

M Mostafa, A Al Fatease, RG Alany, H Abdelkader - Pharmaceutics, 2023 - mdpi.com
Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …

Recent advances in ocular drug delivery systems and targeting VEGF receptors for management of ocular angiogenesis: A comprehensive review

S Narayana, MG Ahmed, BHJ Gowda… - Future Journal of …, 2021 - Springer
Background Angiogenic ocular diseases address the main source of vision impairment or
irreversible vision loss. The angiogenesis process depends on the balance between the pro …

A new era in ocular therapeutics: advanced drug delivery systems for uveitis and neuro-ophthalmologic conditions

KY Wu, K Tan, D Akbar, MY Choulakian, SD Tran - Pharmaceutics, 2023 - mdpi.com
The eye's intricate anatomical barriers pose significant challenges to the penetration,
residence time, and bioavailability of topically applied medications, particularly in managing …

[HTML][HTML] Block copolymer micelles as ocular drug delivery systems

AA Assiri, K Glover, D Mishra, D Waite, LK Vora… - Drug discovery today, 2024 - Elsevier
Highlights•Amphiphilic polymers self-assemble into block copolymer micelles in
solution.•Polymeric micelles have longer and better contact with the ocular …

Absorption enhancement strategies in chitosan-based nanosystems and hydrogels intended for ocular delivery: Latest advances for optimization of drug permeation

I Dmour - Carbohydrate Polymers, 2024 - Elsevier
Ophthalmic diseases can be presented as acute diseases like allergies, ocular infections,
etc., or chronic ones that can be manifested as a result of systemic disorders, like diabetes …