Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the …
F Roth‐Walter, IM Adcock, C Benito‐Villalvilla… - Allergy, 2024 - Wiley Online Library
The accumulation of senescent cells drives inflammaging and increases morbidity of chronic
inflammatory lung diseases. Immune responses are built upon dynamic changes in cell …
inflammatory lung diseases. Immune responses are built upon dynamic changes in cell …
Evaluation of primary DNA damage in young healthy females based on their dietary preferences
DNA damage is known to be associated with many adverse health outcomes, including
cancer and chronic diseases, but also with the process of aging. Empirical evidence has …
cancer and chronic diseases, but also with the process of aging. Empirical evidence has …
Endothelial-to-Mesenchymal Transition in Cardiovascular Pathophysiology
A Singh, KS Bhatt, HC Nguyen, JC Frisbee… - International Journal of …, 2024 - mdpi.com
Under different pathophysiological conditions, endothelial cells lose endothelial phenotype
and gain mesenchymal cell-like phenotype via a process known as endothelial-to …
and gain mesenchymal cell-like phenotype via a process known as endothelial-to …
[HTML][HTML] Effects of moderate ethanol exposure on risk factors for cardiovascular disease and colorectal cancer in adult Wistar rats
AJ Kwon, L Morales, L Chatagnier, J Quigley, J Pascua… - Alcohol, 2024 - Elsevier
While past studies have provided evidence linking excessive alcohol consumption to
increased risk for cardiovascular diseases (CVDs) and colorectal cancer (CRC), existing …
increased risk for cardiovascular diseases (CVDs) and colorectal cancer (CRC), existing …
Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and …
D Nikolopoulos, C Loukogiannaki, G Sentis… - Annals of the …, 2024 - ard.bmj.com
Introduction Systemic lupus erythematosus with antiphospholipid syndrome (SLE-APS)
represents a challenging SLE endotype whose molecular basis remains unknown. Methods …
represents a challenging SLE endotype whose molecular basis remains unknown. Methods …
[PDF][PDF] Cellular Aging and Senescence in Cancer: A Holistic Review of Cellular Fate Determinants
M Tufail, YQ Huang, JJ Hu, J Liang, CY He… - Aging and …, 2025 - researchgate.net
This comprehensive review navigates the complex relationship between cellular aging,
senescence, and cancer, unraveling the determinants of cellular fate. Beginning with an …
senescence, and cancer, unraveling the determinants of cellular fate. Beginning with an …
范可尼贫血: 从遗传疾病到癌症关联的DNA 修复通路探索与治疗展望
史晋宇， 邢琳， 刘世佳， 吕文豪， 张冰琰， 徐立君… - 肿瘤防治研究, 2024 - zlfzyj.com
摘要范可尼贫血(FA) 是一种遗传性疾病, 其特征包括骨髓衰竭, 发育异常和易患癌症.
这种疾病是由基因突变引起的, 导致修复DNA 链间交联(ICLs) 异常. DNA 损伤反应失调会导致 …
这种疾病是由基因突变引起的, 导致修复DNA 链间交联(ICLs) 异常. DNA 损伤反应失调会导致 …
BRCA1 interaction with Non-Canonical DNA Structures: Insights into Genome Maintenance and Disease Mechanisms
Breast Cancer Susceptibility Gene 1 (BRCA1) plays a crucial role in the homologous
recombination (HR) pathway to repair double-stranded breaks (DSBs) in human cells …
recombination (HR) pathway to repair double-stranded breaks (DSBs) in human cells …
脱氧核糖核酸拓扑异构酶Ⅱβ 结合蛋白1 与肿瘤的研究进展
茅静贤， 王佳欣， 严雪冰， 王颖 - 实用临床医药杂志 - jcmp.yzu.edu.cn
脱氧核糖核酸(DNA) 损伤应答(DDR) 是维持内稳态及肿瘤发展重要机制之一. DNA
拓扑异构酶Ⅱβ 结合蛋白1 (TopBP1) 在维持基因组稳定性及调控DDR 相关信号通路中扮演着 …
拓扑异构酶Ⅱβ 结合蛋白1 (TopBP1) 在维持基因组稳定性及调控DDR 相关信号通路中扮演着 …
[PDF][PDF] Evaluation of Primary DNA Damage in Young Healthy Females Based on Their Dietary Preferences. Nutrients 2023, 15, 2218
G Gajski, K Matkovic, L Delic, M Geric - 2023 - academia.edu
DNA damage is known to be associated with many adverse health outcomes, including
cancer and chronic diseases, but also with the process of aging. Empirical evidence has …
cancer and chronic diseases, but also with the process of aging. Empirical evidence has …