C-type lectin-like receptor 2 (CLEC-2, also known as CLEC-1b) is expressed on platelets,
Kupffer cells and other immune cells, and binds to various ligands including the mucin-like …

Oral cancer has become one of the most aggressive types of cancer, killing 140,000 people
worldwide every year. Current treatments for oral cancer include surgery and radiation …

Dopamine (DA), the most abundant human brain catecholaminergic neurotransmitter,
modulates key behavioral and neurological processes in young and senescent brains …

Background Stem cells(SC) functional heterogeneity and its poorly understood aetiology
impedes clinical development of cell-based therapies in regenerative medicine and …

C-type lectin–like receptor 2 (CLEC-2) is a platelet surface–activating receptor with the
prominent involvement in platelet activation, which was found to be associated with the …

Glioblastoma (GBM) is a fatal malignancy caused by dysregulation of cellular signal
transduction. Internalization plays a key role in maintaining signalling balance. Previous …

Podoplanin is a small mucin-like glycoprotein involved in several physiological and
pathological processes in the brain including development, angiogenesis, tumors, ischemic …

Whole‐exome sequencing of two patients with idiopathic complex neurodevelopmental
disorder (NDD) identified biallelic variants of unknown significance within FIBCD1, encoding …

Dementia is a progressive cognitive diminution impeding with normal daily activities that is
constantly on the increase. Currently, the estimated prevalence is 50 million affected people …

Acidosis, a common feature of cerebral ischaemia and hypoxia, plays a key role in these
pathological processes by aggravating the ischaemic and hypoxic injuries. To explore the …