Once thought of primarily as a means to neutralize pathogens or to facilitate feeding,
endocytosis is now known to regulate a wide range of eukaryotic cell processes. Among …

Ligation of the T-cell antigen receptor (TCR) by cognate peptide bound to the Major
Histocompatibility Complex on the surface of an antigen-presenting cell (APC) leads to the …

Tuberculosis (TB) is a lethal multisystem disease that attacks the lungs' first line of defense.
A substantial threat to public health and a primary cause of death is pulmonary TB. This …

Nervous necrosis virus (NNV) has been responsible for mass mortalities in the aquaculture
industry worldwide, with great economic and environmental impact. The present review aims …

Antigen T cell receptors (TCR) recognize antigenic peptides displayed by the major
histocompatibility complex (pMHC) and play a critical role in T cell activation. The levels of …

Overexpression of the EPS15 Homology Domain containing 1 (EHD1) protein has been
linked to tumorigenesis but whether its core function as a regulator of intracellular traffic of …

Grouper (Epinephelus coioides) is an important commercial maricultural fish, which suffers
from nervous necrosis virus (NNV) infection. The molecular mechanisms underlying the …

Background Eggshell speckle phenotype is an important trait in poultry production because
they affect eggshell quality. However, the genetic architecture of speckled eggshells remains …

Aims Increasing evidence has shown that hormone secretion is regulated by endocytosis.
Eps15 homology domain-containing protein 3 (EHD3) is an endocytic-trafficking regulatory …

Epidermal growth factor receptor (EGFR) is a prototype receptor tyrosine kinase and an
oncoprotein in many solid tumors. Cell surface display of EGFR is essential for cellular …