[HTML][HTML] Implication of IL-7 receptor alpha chain expression by CD8+ T cells and its signature in defining biomarkers in aging

MS Shin, HJ Park, J Young, I Kang - Immunity & Ageing, 2022 - Springer
CD8+ T cells play an important role in host defense against infections and malignancies as
well as contribute to the development of inflammatory disorders. Alterations in the frequency …

[HTML][HTML] Novel Synonymous Variant in IL7R Causes Preferential Expression of the Soluble Isoform

R Mackeh, Y El Bsat, A Elmi, H Bibawi… - Journal of Clinical …, 2024 - Springer
Purpose The interleukin-7 receptor (IL-7R) is primarily expressed on lymphoid cells and
plays a crucial role in the development, proliferation, and survival of T cells. Autosomal …

[HTML][HTML] Decreased progenitor TCF1+ T-cells correlate with COVID-19 disease severity

TH Tu, A Grunbaum, F Santinon, A Kazanova… - Communications …, 2024 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, can lead to a severe inflammatory disease
characterized by significant lymphopenia. However, the underlying cause for the depletion …

Prevalence of Selected Polymorphisms of Il7R, CD226, CAPSL, and CLEC16A Genes in Children and Adolescents with Autoimmune Thyroid Diseases

H Borysewicz-Sańczyk… - International Journal of …, 2024 - mdpi.com
Hashimoto's thyroiditis (HT) and Graves' disease (GD) are common autoimmune endocrine
disorders in children. Studies indicate that apart from environmental factors, genetic …

Antisense modulation of IL7R splicing to control sIL7R expression in human CD4+ T cells

G Galarza-Muñoz, D Kennedy-Boone, G Schott… - RNA, 2022 - rnajournal.cshlp.org
The interleukin 7 receptor (IL7R) is strongly associated with increased risk to develop
multiple sclerosis (MS), an autoimmune disease of the central nervous system, and this …

[PDF][PDF] Serum soluble interleukin-7 receptor alpha levels are negatively correlated with the simultaneous activity of antineutrophil cytoplasmic antibody-associated …

T Yoon, JY Pyo, SS Ahn, JJ Song, YB Park, SW Lee - 2023 - core.ac.uk
Serum soluble interleukin-7 receptor alpha levels are negatively correlated with the
simultaneous activity of antineutrophil cyt Page 1 Clinical and Experimental Rheumatology 2022 …

Investigating the Role of Interleukin 7 in Obese African Americans with Type 2 Diabetes

K Webb - 2021 - search.proquest.com
The higher incidence of obesity worldwide, is accompanied by the increasing prevalence of
Type 2 Diabetes (T2D). African Americans compared to other ethnic groups, have a higher …

COMPARATIVE ANALYSIS OF THE EXPRESSION OF THE SOLUBLE IL-7 RECEPTOR IN PATIENTS WITH ARTHROPATHY

AV KOLEROVA, OA ANGELSKAYA… - МЕДИЦИНСКАЯ …, 2023 - elibrary.ru
Arthropathy is one of the most prevalent diseases, which are based on the destruction and
remodeling of cartilage and bone tissue. The inflammation that precedes destruction can be …

Сравнительный анализ экспрессии растворимой формы рецептора IL-7 у пациентов с артропатией

АВ Колерова, ОА Ангельская, ОА Чумасова… - Медицинская …, 2023 - mimmun.ru
Аннотация Артропатии являются одними из самых распространенных заболеваний, в
основе которых лежит деструкция и ремоделирование хрящевой и костной ткани …