Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Exosomes are an extracellular vesicle (EV) subtype that is secreted upon the fusion of
multivesicular bodies (MVBs) with the plasma membrane. Exosomes may participate in …

The plasma membrane is made of glycerophospholipids that separate the inner and outer
parts of the cell. Under physiological conditions, it acts as a barrier and gatekeeper to protect …

Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic
phospholipids in cellular membranes at elevated Ca2+ levels. Through this they act as Ca2+ …

Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience
plasma membrane damage from a multitude of stressors in the extra-and intra-cellular …

As a natural active substance, dihydromyricetin (DHM) has been proven to have good
hepatoprotective activity. However, the therapeutic effect of DHM on liver fibrosis, which has …

Plasma membrane injury can cause lethal influx of calcium, but cells survive by mounting a
polarized repair response targeted to the wound site. Mitochondrial signaling within seconds …

Background and purpose Chronic liver injury, caused by various aetiologies, causes
recurrent tissue damage, culminating in decreased liver regenerative ability and resulting in …

Chronic viral hepatitis B and C and non-alcoholic fatty liver disease (NAFLD) have been
widely acknowledged to be the leading causes of liver cirrhosis and hepatocellular …