Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …

Bacteria are prime cell factories that can efficiently convert carbon and nitrogen sources into
a large diversity of intracellular and extracellular biopolymers, such as polysaccharides …

Recombinant proteins are becoming increasingly important for industrial applications, where
Escherichia coli is the most widely used bacterial host for their production. However, the …

Subunit vaccines are more advantageous than live attenuated vaccines in terms of safety
and scale-up manufacture. However, this often comes as a trade-off to their efficacy. Over …

Cytosolic transport is an essential requirement but a major obstacle to efficient delivery of
therapeutic peptides, proteins and nucleic acids. Current understanding of cytosolic delivery …

Bacteriophages constitute an invaluable biological reservoir for biotechnology and
medicine. The ability to exploit such vast resources is hampered by the lack of methods to …

Materials in nature have fascinating properties that serve as a continuous source of
inspiration for materials scientists. Accordingly, bio-mimetic and bio-inspired approaches …

Abstract Group A Streptococcus (Strep A) is a life-threatening human pathogen with no
licensed vaccine. Here, we used a biopolymer particle (BP) approach to display repeats of …

Liver metastasis represents one of the most frequent malignant diseases with no effective
treatment. Functional reprogramming of Kupffer cells (KCs), the largest population of hepatic …

Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs),
which are important mediators of communication and pathogenesis. OMV uptake by host …