Mechanistic understanding of Cu-based bimetallic catalysts

Y Han, Y Wang, T Ma, W Li, J Zhang… - Frontiers of Chemical …, 2020 - Springer
Copper has received extensive attention in the field of catalysis due to its rich natural
reserves, low cost, and superior catalytic performance. Herein, we reviewed two modification …

Discovery of Quinazolin-4(3H)-ones as NLRP3 Inflammasome Inhibitors: Computational Design, Metal-Free Synthesis, and in Vitro Biological Evaluation

M Abdullaha, S Mohammed, M Ali… - The Journal of …, 2019 - ACS Publications
NLRP3 inflammasome is an important therapeutic target for a number of human diseases.
Herein, computationally designed series of quinazolin-4 (3 H)-ones were synthesized using …

Chemoselective trifluoroethylation reactions of quinazolinones and identification of photostability

S Maiti, J Kim, JH Park, D Nam, JB Lee… - The Journal of …, 2019 - ACS Publications
Herein, we report chemoselective trifluoroethylation routes of unmasked 2-arylquinazolin-4
(3 H)-ones using mesityl (2, 2, 2-trifluoroethyl) iodonium triflate at room temperature …

Oxidant-Controlled C-sp2/sp3–H Cross-Dehydrogenative Coupling of N-Heterocycles with Benzylamines

R Sharma, M Abdullaha… - The Journal of Organic …, 2017 - ACS Publications
Oxidant controlled ionic liquid mediated cross-dehydrogenative coupling (CDC) of
benzylamines with N-heterocycles having sp2 or sp3 carbon resulted in the formation of C …

Quinazolinone Synthesis through Base-Promoted SNAr Reaction of ortho-Fluorobenzamides with Amides Followed by Cyclization

MA Iqbal, L Lu, H Mehmood, DM Khan, R Hua - ACS omega, 2019 - ACS Publications
A transition-metal-free synthesis of quinazolin-4-ones by Cs2CO3-promoted SNAr reaction
of ortho-fluorobenzamides with amides followed by cyclization in dimethyl sulfoxide has …

Electrochemical synthesis of quinazolinone via I 2-catalyzed tandem oxidation in aqueous solution

H Hou, X Ma, Y Lin, J Lin, W Sun, L Wang, X Xu, F Ke - RSC advances, 2021 - pubs.rsc.org
The development of protocols for synthesizing quinazolinones using biocompatible catalysts
in aqueous medium will help to resolve the difficulties of using green and sustainable …

Tandem Reduction, Ammonolysis, Condensation, and Deamination Reaction for Synthesis of Benzothiadiazines and 1-(Phenylsulfonyl)-1H-benzimidazoles

X Yu, Z Ma, W Zhu, H Liu, Z Zhang, Y Liu… - The Journal of …, 2022 - ACS Publications
A novel route for a SnCl2-promoted tandem reduction, ammonolysis, condensation, and
deamination reaction which uses nitrile and 2-nitro-N-phenylbenzenesulfonamide/N-(2 …

Preparation, docking, antimicrobial and cytotoxic activities of 2-arylquinazolinones

N Rahmannejadi, K Zomorodian… - Journal of …, 2017 - publications.article4sub.com
Aims: Recently the use of antifungal drugs in human medicine has been increased,
especially with the advent of AIDS epidemic. The extensive use of antifungal drugs and their …

Syntetické štúdie vedúce k látkam interagujúcim s CAR receptormi

N Palša - 2018 - dspace.cuni.cz
Univerzita Karlova Farmaceutická fakulta v Hradci Králové Katedra organické a
bioorganické chemie Kandidát: Norbert Palša Školiteľ: PharmDr. Marcel Špulák, PhD. Názov …