[HTML][HTML] Rhizoma coptidis and berberine as a natural drug to combat aging and aging-related diseases via anti-oxidation and AMPK activation

Z Xu, W Feng, Q Shen, N Yu, K Yu, S Wang… - Aging and …, 2017 - ncbi.nlm.nih.gov
Aging is the greatest risk factor for human diseases, as it results in cellular growth arrest,
impaired tissue function and metabolism, ultimately impacting life span. Two different …

The genus Stephania (Menispermaceae): chemical and pharmacological perspectives

DK Semwal, R Badoni, R Semwal, SK Kothiyal… - Journal of …, 2010 - Elsevier
The plants of the genus Stephania (Menispermaceae) are widely distributed, and have long
been used in folk medicine for the treatment of various ailments such as asthma …

Role of plant-derived alkaloids against diabetes and diabetes-related complications: a mechanism-based approach

A Kumar, S Aswal, RB Semwal, A Chauhan… - Phytochemistry …, 2019 - Springer
Diabetes mellitus is a metabolic disorder of multiple etiologies, characterized by chronic
hyperglycemia together with the disturbance of carbohydrate, fat, protein metabolism …

Palmatine as an agent against metabolic syndrome and its related complications: a review

SO Ekeuku, KL Pang, KY Chin - Drug design, development and …, 2020 - Taylor & Francis
Palmatine is a naturally occurring isoquinoline alkaloid with various pharmacological
properties. Given its antioxidant and anti-inflammatory properties, palmatine may be able to …

Alkaloids in genus stephania (Menispermaceae): a comprehensive review of its ethnopharmacology, phytochemistry, pharmacology and toxicology

M Wang, XM Zhang, X Fu, P Zhang, WJ Hu… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Approximately 60 species of the genus Stephania
(Menispermaceae) are distributed worldwide. Among these, 39 species are located in South …

Effect of Rhizoma coptidis (Huang Lian) on Treating Diabetes Mellitus

B Pang, XT Yu, Q Zhou, TY Zhao… - Evidence‐Based …, 2015 - Wiley Online Library
The rapidly increasing diabetes mellitus (DM) is becoming a major public health issue
globally; considerable progress has been made in the field of western hypoglycemic drug …

Ethnomedicinal investigation of medicinal plants of Chakrata region (Uttarakhand) used in the traditional medicine for diabetes by Jaunsari tribe

A Kumar, S Aswal, A Chauhan, RB Semwal… - Natural products and …, 2019 - Springer
The Himalayan region is the treasure house of natural wealth, particularly of medicinal and
aromatic plants. These plants are used by the Indian traditional healers for the past many …

Palmatine inhibits growth and invasion in prostate cancer cell: Potential role for rpS6/NFκB/FLIP

HG Hambright, IS Batth, J Xie, R Ghosh… - Molecular …, 2015 - Wiley Online Library
Novel agents are desperately needed for improving the quality of life and 5‐year survival to
more than 30% for metastatic castrate‐resistant prostate cancer. Previously we showed that …

[PDF][PDF] Phytochemicals in antidiabetic drug discovery

R Singh, T Arif, I Khan, P Sharma - J. Biomed. Ther. Sci, 2014 - academia.edu
Management of diabetes mellitus is a challenge for clinicians. Uncontrolled hyperglycemia
increases the risk of microvascular and macrovascular complications, damaging the body …

Cytotoxic Bisbenzylisoquinoline Alkaloids from Stephania epigaea

JJ Lv, M Xu, D Wang, HT Zhu, CR Yang… - Journal of natural …, 2013 - ACS Publications
Six new bisbenzylisoquinoline alkaloids (1–6) and seven known compounds (8–14) were
isolated from the tubers of Stephania epigaea, in addition to the major alkaloid …