The human genome is pervasively transcribed, producing a majority of short and long
noncoding RNAs (lncRNAs) that can influence cellular programs through a variety of …

A growing number of variants associated with risk for neurodevelopmental disorders have
been identified by genome-wide association and whole genome sequencing studies. As …

Background Autism spectrum disorder (ASD) is a neurodevelopmental condition
characterized by impaired social and communication skills, restricted interests, and …

Little is known about the role of non-coding regions in the etiology of autism spectrum
disorder (ASD). We examined three classes of non-coding regions: human accelerated …

Abstract Autism Spectrum Disorders (ASD) are a group of neurodevelopmental disorders
(NDDs) characterized by difficulties in social interaction and communication, repetitive …

δ-catenin is expressed in excitatory synapses and functions as an anchor for the
glutamatergic AMPA receptor (AMPAR) GluA2 subunit in the postsynaptic density. The …

Background Autism spectrum disorder (ASD) is a common neurodevelopmental disease,
characterized by deficits in social communication, restricted and repetitive behaviours, and …

Neurodevelopmental disorders have been associated with genetic mutations that affect
cellular function, including chromatin regulation and epigenetic modifications. Recent …

Delta-catenin (CTNND2) is an adhesive junction associated protein belonging to the family
of p120 catenins. The human gene is located on the short arm of chromosome 5, the region …

Schizophrenia (SCZ) is a complex psychiatric disorder with unclear biological mechanisms.
Spectrins, cytoskeletal proteins linked to neurodevelopmental disorders, are regulated by …