Objectives To determine the effect on mortality of selective digestive decontamination,
selective oropharyngeal decontamination, and topical oropharyngeal chlorhexidine in adult …

Candida albicans is a common microorganism in the intestine. However, invasive C.
albicans infection has emerged as a life-threatening disease in recent years. The mortality …

Secondary peritonitis remains associated with high mortality and morbidity rates. Treatment
of secondary peritonitis is challenging even in modern medicine. Surgical intervention for …

Background Invasive fungal infections acquired in the intensive care unit (AFI) are life-
threating complications of critical illness. However, there is no consensus on antifungal …

This study aims to determine whether abdominal microbial profiles in early severe
secondary peritonitis are associated with ongoing infection or death. The study is performed …

The impact of antimicrobials on the human microbiome and its relationship to human health
are of great interest. How antimicrobial exposure might drive change within specific …

Selective digestive decontamination (SDD) regimens, variously constituted with topical
antibiotic prophylaxis (TAP) and protocolized parenteral antibiotic prophylaxis (PPAP) …

Purpose To estimate the direct and indirect (contextual) effects of the factorized constituents
of selective digestive decontamination and selective oropharyngeal decontamination …

To date, despite limited prospective validation, clinical models targeted at early identification
of patients at risk to develop invasive candidiasis represent a major advance in the …

Abstract Background Whether Candida interacts with Gram-positive bacteria, such as
Staphylococcus aureus, coagulase negative Staphylococci (CNS) and Enterococci, to …