Pushing the limits of the scanning mechanism for initiation of translation
M Kozak - Gene, 2002 - Elsevier
Selection of the translational initiation site in most eukaryotic mRNAs appears to occur via a
scanning mechanism which predicts that proximity to the 5′ end plays a dominant role in …
scanning mechanism which predicts that proximity to the 5′ end plays a dominant role in …
Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
ContextGiven the numerous, yet inconsistent, reports of genetic variants being associated
with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS …
with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS …
Quantitative analysis of mammalian translation initiation sites by FACS‐seq
WL Noderer, RJ Flockhart, A Bhaduri… - Molecular systems …, 2014 - embopress.org
An approach combining fluorescence‐activated cell sorting and high‐throughput DNA
sequencing (FACS‐seq) was employed to determine the efficiency of start codon recognition …
sequencing (FACS‐seq) was employed to determine the efficiency of start codon recognition …
A Graves' Disease-Associated Kozak Sequence Single-Nucleotide Polymorphism Enhances the Efficiency of CD40 Gene Translation: A Case for Translational …
EM Jacobson, E Concepcion, T Oashi, Y Tomer - Endocrinology, 2005 - academic.oup.com
We analyzed the mechanism by which a Graves' disease-associated C/T polymorphism in
the Kozak sequence of CD40 affects CD40 expression. CD40 expression levels on B cells in …
the Kozak sequence of CD40 affects CD40 expression. CD40 expression levels on B cells in …
No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age
… , Thrombosis, and Vascular Biology Italian Study … - Circulation, 2003 - Am Heart Assoc
Background—We investigated the association between 9 polymorphisms of genes encoding
hemostasis factors and myocardial infarction in a large sample of young patients chosen …
hemostasis factors and myocardial infarction in a large sample of young patients chosen …
Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: evidence from atomic force microscopy …
JH Rand, XX Wu, AS Quinn, PP Chen… - The American journal of …, 2003 - Elsevier
The antiphospholipid (aPL) syndrome is an autoimmune condition that is marked by
recurrent pregnancy losses and/or systemic vascular thrombosis in patients who have …
recurrent pregnancy losses and/or systemic vascular thrombosis in patients who have …
A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss
N Bogdanova, J Horst, M Chlystun… - Human molecular …, 2007 - academic.oup.com
We sought to verify whether variation in the promoter of the gene encoding placental
anticoagulant protein annexin A5 (ANXA5) represents a risk factor for recurrent pregnancy …
anticoagulant protein annexin A5 (ANXA5) represents a risk factor for recurrent pregnancy …
Determination of the functionality of common APOA5 polymorphisms
PJ Talmud, J Palmen, W Putt, L Lins… - Journal of Biological …, 2005 - ASBMB
Common variants of APOA5 have consistently shown association with differences in plasma
triglyceride (TG) levels. These single nucleotide polymorphisms (SNPs) fall into three …
triglyceride (TG) levels. These single nucleotide polymorphisms (SNPs) fall into three …
[HTML][HTML] Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges
S Martin, V Nicaud, SE Humphries, PJ Talmud - Biochimica et Biophysica …, 2003 - Elsevier
The aim of this study was to investigate the influence of APOA5 variants on fasting lipids and
to the response to both an oral fat tolerance test (OFTT) and an oral glucose tolerance test …
to the response to both an oral fat tolerance test (OFTT) and an oral glucose tolerance test …