One of the early symptoms of chronic venous disease (CVD) is varicose veins (VV) of the
lower limbs. There are many etiological environmental factors influencing the development …

Necroptosis is a pivotal contributor to the pathogenesis of various human diseases,
including those affecting the nervous system, cardiovascular system, pulmonary system, and …

Being the sixth most diagnosed cancer and the fourth leading cause of cancer-related
deaths worldwide, liver cancer is considered as a serious disease with a high prevalence …

Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-
associated fatty liver disease (MAFLD). However, the mechanisms underlying their …

Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …

Aims Ovarian ischemia–reperfusion (I/R) injury is a phenomenon that necessitates urgent
intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young …

Twelve new hybrid compounds of Esculetin with nitric oxide (NO) donors and/or
mitochondrial targeting groups were designed, synthesized, and evaluated for their anti …

Autism spectrum disorder (ASD) is a multifaceted developmental condition that first appears
in infancy. The condition is characterized by recurrent patterns in behavior and impairments …

Phytocoumarins exhibit a range of biological activities, including antibacterial, anti-
inflammatory, antiradical, oncolytic, and reduction of monoamine oxidase B effects. These …

(1) Malignant melanomas are dangerous skin cancers, and the treatment of melanomas with
various cytostatic drugs often causes side effects and after their prolonged use resistance to …