Biological activities of hydrazone derivatives

S Rollas, Ş Güniz Küçükgüzel - Molecules, 2007 - mdpi.com
There has been considerable interest in the development of novel compounds with
anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, anti-malarial …

Mini-review of the importance of hydrazides and their derivatives—Synthesis and biological activity

SN Mali, BR Thorat, DR Gupta, A Pandey - Engineering proceedings, 2021 - mdpi.com
Organic acid hydrazides include a vast group of organic derivatives of hydrazines containing
the active functional group (-C (= O) NHNH2). Acid hydrazones were important bidentate …

Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives

M Taha, SAA Shah, M Afifi, S Imran, S Sultan… - Bioorganic …, 2018 - Elsevier
We have synthesized seventeen Coumarin based derivatives (1–17), characterized by 1
HNMR, 13 CNMR and EI-MS and evaluated for α-glucosidase inhibitory potential. Among …

Synthesis, structure, and bioactivity of N′-substituted benzylidene-3, 4, 5-trimethoxybenzohydrazide and 3-acetyl-2-substituted phenyl-5-(3, 4, 5-trimethoxyphenyl)-2 …

L Jin, J Chen, B Song, Z Chen, S Yang, Q Li… - Bioorganic & medicinal …, 2006 - Elsevier
Some 3-acetyl-2-substituted phenyl-5-(3, 4, 5-trimethoxyphenyl)-2, 3-dihydro-1, 3, 4-
oxadiazole derivatives were synthesized by cyclization reaction of N′-substituted …

Metal complexes of hydrazones and their biological, analytical and catalytic applications: A review

MME Shakdofa, MH Shtaiwi, N Morsy… - Main Group …, 2014 - content.iospress.com
This is the first comprehensive review of the biological activity of hydrazone-transition metal
complexes. Hydrazone complexes gained much attention because of their antifugial …

Synthesis, structural activity relationship and anti-tubercular activity of novel pyrazoline derivatives

MA Ali, M Shaharyar, AA Siddiqui - European journal of medicinal chemistry, 2007 - Elsevier
In the present investigation, a series of 5-(-4-(substituted) phenyl)-3-(4-hydroxy-3-
methylphenyl)-4, 5-dihydro-1H-1-pyrazolyl-2-toluidino methane thione and 5-(substituted) …

Synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory potential of hydrazide based Schiff bases

F Rahim, H Ullah, M Taha, A Wadood, MT Javed… - Bioorganic …, 2016 - Elsevier
To discover multifunctional agents for the treatment of Alzheimer's disease, a series of
hydrazide based Schiff bases were designed and synthesized based on multitarget-directed …

Synthesis and in vitro antimycobacterial activity of N1-nicotinoyl-3-(4′-hydroxy-3′-methyl phenyl)-5-[(sub) phenyl]-2-pyrazolines

M Shaharyar, AA Siddiqui, MA Ali, D Sriram… - Bioorganic & medicinal …, 2006 - Elsevier
A series of N1-nicotinoyl-3-(4′-hydroxy-3′-methyl phenyl)-5-(substituted phenyl)-2-
pyrazolines were synthesized by the reaction between isoniazid (INH) and chalcones and …

Synthesis, spectroscopic characterization and dyeing performance of novel bis azo dyes derived from benzidine

AZ Omar, MA El-Rahman, EA Hamed, SK El-Sadany… - Scientific Reports, 2023 - nature.com
Benzidine was coupled with ethyl cyanoacetate, and malononitrile, to give azo-hydrazo
products which in turn were cyclized by using hydrazine and phenyl hydrazine to give 4, 4' …

Synthesis, antitubercular evaluation and 3D-QSAR study of N-phenyl-3-(4-fluorophenyl)-4-substituted pyrazole derivatives

RC Khunt, VM Khedkar, RS Chawda… - Bioorganic & medicinal …, 2012 - Elsevier
As a part of our ongoing research to develop novel antitubercular agents, a series of N-
phenyl-3-(4-fluorophenyl)-4-substituted pyrazoles have been synthesized and tested for …