Targeting the blood-brain barrier to prevent sepsis-associated cognitive impairment

DC Nwafor, AL Brichacek… - Journal of central …, 2019 - journals.sagepub.com
Sepsis is a systemic inflammatory disease resulting from an infection. This disorder affects
750 000 people annually in the United States and has a 62% rehospitalization rate. Septic …

In silico evaluation of gadofosveset pharmacokinetics in different population groups using the Simcyp® simulator platform

M Spanakis, K Marias - In Silico Pharmacology, 2014 - Springer
Abstract Purpose Gadofosveset is a Gd-based contrast agent used for magnetic resonance
imaging (MRI). Gadolinium kinetic distribution models are implemented in T1-weighted …