Andrographis paniculata (A. paniculata) is a medicinal plant traditionally used as anti-
inflammation and anti-bacteria herb. Andrographolide, the major active component of A …

The diterpene lactone andrographolide, isolated from Andrographis paniculata, has been
proven to possess several important protective biological activities, including antioxidant …

Abstract Background Andrographolide (Andro), a diterpenoid lactone, has been used for
treatment of various cancers with less adverse effects. However, the underlying mechanisms …

Andrographis paniculata has long been part of the traditional herbal medicine system in
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …

Breast cancer is the most frequent cancer in women; however, it is curable in most cases (up
to 80%) when detected and treated at an early non-metastatic stage. Nanotechnology has …

Terpenes and terpenoids are the largest groups of plant secondary metabolites. However,
unlike polyphenols, they are rarely associated with geroprotective properties. Here we …

Ethnopharmacological relevance Synthetic drugs used for cancer treatment have side
effects that may be immunosupressive, can cause liver, kidney and cardiac toxicity, and …

Andrographolide is a labdane diterpenoid isolated from Andrographis paniculata and
traditionally used in Chinese and Indian medicine. Reported effects include anti-bacterial …

Background Ferroptosis, a form of regulated cell death by lipid peroxidation, was currently
considered as a key factor affecting the occurrence and progression in various cancers …

Andrographis paniculata (AP) is a traditional medicinal plant with many pharmacological
activities, including anti-inflammatory, antimicrobial, immunity stimulation and so on. Several …